[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545918":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":30,"studyPopulation":31,"armGroups":26,"interventions":26,"overallOfficials":32,"centralContacts":36,"locations":41,"responsibleParty":58,"collaborators":26,"id":62,"slug":26,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":26,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":26,"briefSummary":75,"conditions":76,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":26},[9,13],{"measure":10,"description":11,"timeFrame":12},"The proportion of drug-resistent epilepsy","We defined drug-resistant cases as those patients who have failed two or more trials of broad-spectrum ASMs or those otherwise indicated in IGE syndromes","through study completion, an average of 1 year",{"measure":14,"description":15,"timeFrame":12},"The proportion of seizure freedom","We defined seizure freedom according to the International League Against Epilepsy (ILAE) definition",[17,20,23],{"measure":18,"description":19,"timeFrame":12},"The proportion of psychiatric comorbidity","The psychiatric comorbidities mainly include anxiety and depression, which are evaluated by Hamilton anxiety scale and Hamilton depression scale, respectively.",{"measure":21,"description":22,"timeFrame":12},"The proportion of psychosocial outcome","such as university entrance, marry",{"measure":24,"description":25,"timeFrame":12},"The proportion of seizure relapse after antiseizure medication withdrawn","Antiseizure medication withdrawn should be recommended by epilepsy experts",null,{"allocation":26,"interventionModel":26,"interventionModelDescription":26,"primaryPurpose":26,"observationalModel":28,"timePerspective":29,"maskingInfo":26},"COHORT","PROSPECTIVE","the Long-term prognosis include the rate of drug-resistent epilepsy, relapse after drug withdrawn, common comorbidities such as mood disorders, attention deficit hyperactivity disorder (ADHD) and learning disabilities.","Patients are consecutively and prospectively recruited from epilepsy center and clinics",[33],{"name":34,"affiliation":5,"role":35},"Chunhong Shen","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+86 0571 87783872","shen_neurology@zju.edu.cn",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"2nd Affiliated Hospital, School of Medicine, Zhejiang University, China","RECRUITING","Hangzhou","Zhejiang","310000","China","CN",{"type":51,"coordinates":52},"Point",[53,54],120.16142,30.29365,{"lat":54,"lon":53},[57],{"name":34,"role":38,"phone":39,"phoneExt":26,"email":40},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Shen Chun-Hong","Associate Senior Doctor","100545918",false,"NCT06388174","Idiopathic Generalized Epilepsy Syndromes","Idiopathic Generalized Epilepsy Syndromes: Clinical Features and Long-term Outcomes","Inclusion Criteria:\n\n* Patients are consecutively and prospectively enrolled from epilepsy center, with newly diagnosed epilepsy or established epilepsy.\n* Patients have a diagnosis of idiopathic generalized epilepsy (IGE), according to the 2022 diagnostic criteria.\n* Comprehensive clinical information is collected, and 24 hour video-electroencephalography is performed.\n* Sign the informed consent forms.\n\nExclusion Criteria:\n\n* Other epilepsy syndromes are considered during follow-up, such as genetic generalized epilepsy.\n* Lost to follow-up","ALL","4 Years","40 Years",{"count":72,"type":73},200,"ESTIMATED","OBSERVATIONAL","The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.\n\nAccording to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.",[77,78],"Epilepsy","Epilepsy, Idiopathic Generalized","2025-08-20",{"date":81,"type":82},"2025-08-27","ACTUAL",{"date":84,"type":82},"2023-01-01",{"date":86,"type":73},"2033-12-31",{"name":60,"class":6},1]