About this trial

Following whole blood stimulation with mesenchymal stem cell derived exosomes, immune phenotype, cytokine release and mRNA expression patterns from critically ill patients with COVID-19 will be determined.

Eligibility criteria

Qualifiers

Critically ill COVID-19 patients with lung dysfunction

COVID-19 WHO severity degree >= 4, ARDS (WHO Definition 13 March 2020)

Body weight > 50 kg

Informed consent

Disqualifiers

Pregnant or breast feeding women

Trial design

Treatments tested in this trial

  • Application of exosomes in a whole blood assay

Treatment groups

No treatment groups listed

Locations

1
Ulm University Hospital, Clinic of Anesthesiology and Intensive Care Medicine89070, Ulm Germany

Sponsors and collaborators

University of Ulm

Lead sponsor