About this trial
The investigators hypothesize that cardiovascular and metabolic alterations can occur in patients with adrenal adenomas and possible Autonomous Cortisol Secretion (pACS). Investigators hypothesize that adrenalectomy in selected patients, following the 2016 European Congress of Endocrinology (ECE) guidelines, can improve metabolic parameters and cardiovascular risks and features.
Eligibility criteria
Qualifiers
Incidentally detected adrenal mass
Disqualifiers
Patients with overt Cushing's syndrome, pheochromocytoma, Conn syndrome, adrenocortical carcinoma, late-onset congenital adrenal hyperplasia, adrenal metastasis and adrenal hemorrhage
Patients taking medications influencing glucocorticoid production or metabolism
Patients with psychiatric diseases or alcohol abuse
Pregnancy
Trial design
Treatments tested in this trial
- Adrenalectomy
Treatment groups
Locations
1Sponsors and collaborators
University of Roma La Sapienza
Lead sponsor