About this trial

The aim of the present study is to investigate intra-operative changes in markers of myocardial injury during ischemia and reperfusion, comparing three methods of myocardial protection; St. Thomas' cold crystalloid cardioplegia, Calafiore warm blood cardioplegia, or modified del Nido cold blood cardioplegia in routine coronary artery bypass grafting procedures.

Eligibility criteria

Qualifiers

All consecutive patients undergoing elective primary coronary artery bypass grafting will be enrolled in this study.

Disqualifiers

Patients will be excluded from this study if they had suffered from previous myocardial infarction, had reduced ejection fraction or were undergoing combined or repeated surgery

Trial design

Treatments tested in this trial

  • The intervention is the use of a specific cardioplegia solution for myocardial protection

Treatment groups

30 Participants
are divided into 3 treatment groups

Locations

1
Damascus University Cardiac Surgery HospitalRawda, DamascusRif-dimashq Governorate, Syria

Sponsors and collaborators

Damascus University

Lead sponsor