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Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence

ConditionsPostoperative PainFlare upFlare Up, Symptom
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorMinia University

About this trial

This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18-60 (adults only)

multiple-rooted with multiple root canal.

Permanent teeth with mature apex and complete root formation.

Without root caries.

Disqualifiers

single root canals or double root.

Root canal calcifications.

Root resorption or fracture.

Previously root canal treated teeth.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Chitosan Nanoparticles Irrigant

    Other intervention

    using Chitosan Nanoparticles irrigant as a final irrigation solution.

  • aloe vera nanoparticles irrigant

    Other intervention

    using Aloe Vera Nanoparticles irrigant as a final irrigation solution.

  • Diode Laser Activation

    Device

    activation of nanoparticles irrigants using diode laser

  • ultrasonic activator

    Device

    activation of nanoparticles irrigants using ultrasonic activator

Treatment groups

64 Participants
are divided into 4 treatment groups
Group A: GROUP IExperimental treatment 2 interventions
Group B: GROUP IIExperimental treatment 2 interventions
Group C: GROUP IIIExperimental treatment 2 interventions
Group D: GROUP IVExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

postoperative pain intensity Postoperative pain is to be assessed using visual analog scale (VAS), A scale from (0 to 10) where "0" means no pain and "10 means a severe pain that has never faced before.

Patients will be contacted by phone at 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.

Time frame
[Time Frame: 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.]

Secondary outcomes

1

Flare-Up Incidence Flare-up is assessed through asking the patient to notify the investigator if any sudden severe pain or swelling takes place.

This could require an unscheduled emergency visit or prescription of additional medication.

Time frame
[Time Frame: Within 7 days post-treatment)

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Minia University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: