Impact of New Hormone Replacement Therapy After Menopause on Heart Health in Women

ConditionsHormone Replacement Therapy Cardiovascular Diseases Hormone Replacement Therapy, Post-Menopausal Menopause

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexFemale

Age45-75

SponsorHeinrich-Heine University, Duesseldorf

About this trial

This prospective registry study investigates the impact of new hormone replacement therapy (HRT) delivery methods, such as creams, gels, and sprays, on cardiovascular risk in postmenopausal women. Menopause-related estrogen deficiency leads to metabolic and vascular changes that increase atherosclerosis and cardiovascular events. This study hypothesizes that new HRT forms may reduce cardiovascular risk in high-risk women."

Eligibility criteria

Qualifiers

Age 45-75 years

Score 2 > 5%

Or existing coronary heart disease

Or cAVK

Disqualifiers

Age <45 years / > 75 years

Existing cancer

Language barrier, inability to provide informed consent

GFR <30 ml/min or dialysis

Trial design

Treatments tested in this trial

Not listed

Trial groups

2,725 Participants

are grouped into 2 trial groups

Locations

Clinic for Cardiology, Angiology and Intensive Care at Charité Mitte Berlin Berlin Germany

University Hospital Duesseldorf40225, Düsseldorf Germany

Sponsors and collaborators

Heinrich-Heine University, Duesseldorf

Lead sponsor

Source ClinicalTrials.gov