Impact of Yo-Yo Sleep on Cardiometabolic Health

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-49
SponsorColumbia University

About this trial

The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).

Eligibility criteria

Qualifiers

Aged 18 to 49 years

BMI 20-29.9 kg/m2

Habitually sleeping 7-9 hours/night without sleep aids or naps

Disqualifiers

Sleep disorders

Psychiatric disorders (including eating disorders) and seasonal affective disorder

Pregnancy (current/prior year)

Breastfeeding

Trial design

Treatments tested in this trial

  • Intermittent Short Sleep (ISS)
  • Social Jetlag (SJL)
  • Sustained Adequate Sleep (SAS)

Treatment groups

72 Participants
are divided into 3 treatment groups

Locations

1
Columbia University Irving Medical Center10032, New YorkNew York, United States

Sponsors and collaborators

Columbia University

Lead sponsor

Icahn School of Medicine at Mount Sinai

Collaborator

University of Colorado, Denver

Collaborator

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator