Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age23-45
SponsorNew York State Psychiatric Institute

About this trial

This study examines the impact of Auxilio Brasil (AB), a cash transfer program to mothers of school-age children, on resource-deprived populations in Brazil and its protective effects on child neurodevelopment and mental health. The investigators will conduct a randomized clinical trial (RCT) among those already receiving AB in which 300 families will be randomized in a 1:1 ratio to receive either a high ($40/month) or low ($2/month) supplemental transfer for 2 years. Three hundred children (index child participants; 7-10 years old) will be enrolled across both study arms. Additionally, up to 150 siblings ("sibling participants;" 7-10 years old) will be enrolled. Eligible families who decide to participate will sign a study-specific informed consent (mother) and assent (child) form. The UNIFESP team will conduct the respective assessments at baseline, approximately 8- and 16- months, 24-months and approximately 6-months post-RCT.

Aim 1: Determine the impact of high vs low cash transfers on children's exposure to adversities (ACEs) and neurodevelopment.

Aim 2: Determine the impact of cash transfers on children's inflammatory markers and HPA activity/cortisol.

Exploratory Aim: The investigators will explore (i) whether sex/gender of the children moderates the pathways in the above mediation model; and (ii) whether cash transfer-related effects persist 6 months post-RCT.

Eligibility criteria

Qualifiers

Age 23-45 years old

Receiving AB cash transfers

Has at least two or more children ages 7- 10 years old at time of recruitment (up to 4 children per family)

Able to consent

Disqualifiers

Age 7-10 years old

Intellectual Disability

Does not reside in same household as the mother

Major Axis I disorder (e.g., Autism, Schizophrenia, Bipolar)

Trial design

Treatments tested in this trial

  • Supplemental cash transfer

Treatment groups

450 Participants
are divided into 2 treatment groups

Locations

2
Brazil
UNIFESP04023, São PauloSão Paulo, Brazil
United States
New York State Psychiatric Institute10032, New YorkNew York, United States

Sponsors and collaborators

New York State Psychiatric Institute

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator