[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100475974":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":37,"locations":42,"responsibleParty":74,"collaborators":77,"id":81,"slug":18,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":18,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":18,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":18,"overallStatus":60,"whyStopped":18,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"New York State Psychiatric Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","High supplemental transfer: $40 a month",[13],"Other: Supplemental cash transfer",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Low supplemental transfer: $2 a month",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Supplemental cash transfer","Supplemental cash transfer ($40\u002Fmonth)",[9],[25,28,31,34],{"name":26,"affiliation":5,"role":27},"Cristiane Duarte, PhD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":27},"Andrea Jackowsi, PhD","Federal University of São Paulo",{"name":32,"affiliation":33,"role":27},"Jonathan Posner, MD","Duke University",{"name":35,"affiliation":5,"role":36},"Tenneill Murray, MPH","STUDY_DIRECTOR",[38],{"name":26,"role":39,"phone":40,"phoneExt":18,"email":41},"CONTACT","646-774-5801","cristiane.duarte@nyspi.columbia.edu",[43,58],{"facility":5,"status":44,"city":45,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"NOT_YET_RECRUITING","New York","10032","United States",{"type":49,"coordinates":50},"Point",[51,52],-74.00597,40.71427,{"lat":52,"lon":51},[55],{"name":26,"role":39,"phone":56,"phoneExt":18,"email":57},"(646)774-5801","Cristiane.Duarte@nyspi.columbia.edu",{"facility":59,"status":60,"city":61,"state":61,"zip":62,"country":63,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"UNIFESP","RECRUITING","São Paulo","04023","Brazil",{"type":49,"coordinates":65},[66,67],-46.63611,-23.5475,{"lat":67,"lon":66},[70],{"name":71,"role":39,"phone":72,"phoneExt":18,"email":73},"Andrea Jackowski, PhD","+55-11985855785","andrea.jackowski@gmail.com",{"type":27,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Cristiane Duarte","Ruane Professor for the Implementation of Science for Child and Adolescent mental Health (in Psychiatry) at CUMC",[78],{"name":79,"class":80},"National Institute of Mental Health (NIMH)","NIH","100475974",false,"NCT05477901","Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)","Mental Health and Bolsa Familia: A Mechanistically Focused Clinical Trial of a Cash Transfer Intervention on Child Brain, Behavior, and Mental Health","Mother:\n\nInclusion Criteria:\n\n1. Age 23-45 years old\n2. Receiving AB cash transfers\n3. Has at least two or more children ages 7- 10 years old at time of recruitment (up to 4 children per family)\n4. Able to consent\n\nExclusion Criteria:\n\n1\\. Mother and child do not reside in same household\n\nChild:\n\nInclusion Criterion\n\n1. Age 7-10 years old\n2. Intellectual Disability\n\nExclusion Criterion\n\n1. Does not reside in same household as the mother\n2. Major Axis I disorder (e.g., Autism, Schizophrenia, Bipolar)\n3. Severe Disability\n4. MRI contradictions (index child only)","ALL","23 Years","45 Years",{"count":91,"type":92},450,"ESTIMATED","INTERVENTIONAL",[95],"NA","This study examines the impact of Auxilio Brasil (AB), a cash transfer program to mothers of school-age children, on resource-deprived populations in Brazil and its protective effects on child neurodevelopment and mental health. The investigators will conduct a randomized clinical trial (RCT) among those already receiving AB in which 300 families will be randomized in a 1:1 ratio to receive either a high ($40\u002Fmonth) or low ($2\u002Fmonth) supplemental transfer for 2 years. Three hundred children (index child participants; 7-10 years old) will be enrolled across both study arms. Additionally, up to 150 siblings (\"sibling participants;\" 7-10 years old) will be enrolled. Eligible families who decide to participate will sign a study-specific informed consent (mother) and assent (child) form. The UNIFESP team will conduct the respective assessments at baseline, approximately 8- and 16- months, 24-months and approximately 6-months post-RCT.\n\nAim 1: Determine the impact of high vs low cash transfers on children's exposure to adversities (ACEs) and neurodevelopment.\n\nAim 2: Determine the impact of cash transfers on children's inflammatory markers and HPA activity\u002Fcortisol.\n\nExploratory Aim: The investigators will explore (i) whether sex\u002Fgender of the children moderates the pathways in the above mediation model; and (ii) whether cash transfer-related effects persist 6 months post-RCT.",[98,99,100,101],"Inflammation","HPA","CBCL","Family Relations","2026-04-20",{"date":104,"type":105},"2026-04-23","ACTUAL",{"date":107,"type":105},"2025-05-28",{"date":109,"type":92},"2029-01-31",{"name":5,"class":6},2]