[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574895":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":26,"studyPopulation":27,"armGroups":28,"interventions":22,"overallOfficials":35,"centralContacts":40,"locations":48,"responsibleParty":140,"collaborators":22,"id":142,"slug":22,"hasResults":143,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":22,"eligibilityCriteria":147,"healthyVolunteers":143,"sex":148,"minAge":149,"maxAge":22,"enrollmentInfo":150,"targetDuration":22,"studyType":153,"phases":22,"briefSummary":154,"conditions":155,"keywords":22,"overallStatus":106,"whyStopped":22,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":166},{"fullName":5,"class":6},"Abiomed Inc.","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":22},[9,13],{"measure":10,"description":11,"timeFrame":12},"Investigate deposits and biomaterial after use of pump","investigate Impella CP after use regarding deposits and biomaterial","through study completion, at least 5 days",{"measure":10,"description":14,"timeFrame":15},"investigate Impella 5.5 pumps after use regarding deposits and biomaterial","through study completion, at least 25 days",[17,20],{"measure":18,"description":19,"timeFrame":12},"Relation deposits and biomaterial to clinical events","By correlating patient data, such as medical history and Impella CP related blood parameters, with the findings from our pump analysis, potential connections between medication, diseases, comorbidities, and deposits on the pump can be identified.",{"measure":18,"description":21,"timeFrame":15},"By correlating patient data, such as medical history and Impella 5.5 related blood parameters, with the findings from our pump analysis, potential connections between medication, diseases, comorbidities, and deposits on the pump can be identified.",null,{"allocation":22,"interventionModel":22,"interventionModelDescription":22,"primaryPurpose":22,"observationalModel":24,"timePerspective":25,"maskingInfo":22},"OTHER","RETROSPECTIVE","The Impella heart pump supports patients in cardiogenic shock for various reasons and has passed safety and biocompatibility evaluations. The planned investigation aims to further analyze cell and protein adhesion on these pumps and the effects of their prolonged use, especially in scenarios like bridge-to-transplant, recognizing preclinical testing limitations.","Patients treated with Impella CP or Impella 5.5 heart pump due to severe acute heart failure by any cause (e.g. cardiogenic shock in acute myocardial infarction, cardiac arrest, myocarditis or in relation to cardiac surgery).",[29,32],{"label":30,"type":22,"description":31,"interventionNames":22},"Impella CP","Patients treated with Impella CP heart pump for more than 4 days due to severe acute heart failure by any cause",{"label":33,"type":22,"description":34,"interventionNames":22},"Impella 5.5","Patients treated with Impella 5.5 heart pump for more than or equal to 25 days due to severe acute heart failure by any cause",[36],{"name":37,"affiliation":38,"role":39},"Pia Lanmüller, MD","Deutsches Herzzentrum der Charité","PRINCIPAL_INVESTIGATOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":22,"email":45},"Kirstin Starke, Director","CONTACT","+49 241 88600","RA-PumpReturnEMailAr@ITS.JNJ.com",{"name":47,"role":43,"phone":22,"phoneExt":22,"email":22},"Christian Cremer, CPM",[49,66,79,92,104,116,128],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Universitätsklinikum Heidelberg","NOT_YET_RECRUITING","Heidelberg","Baden-Wurttemberg","69120","Germany","DE",{"type":58,"coordinates":59},"Point",[60,61],8.69079,49.40768,{"lat":61,"lon":60},[64],{"name":65,"role":39,"phone":22,"phoneExt":22,"email":22},"Anna Meyer, MD",{"facility":67,"status":51,"city":68,"state":69,"zip":70,"country":55,"countryCode":56,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Universitätsklinikum Düsseldorf","Düsseldorf","North Rhine-Westphalia","40225",{"type":58,"coordinates":72},[73,74],6.77927,51.22319,{"lat":74,"lon":73},[77],{"name":78,"role":39,"phone":22,"phoneExt":22,"email":22},"Amin Polzin, MD",{"facility":80,"status":51,"city":81,"state":82,"zip":83,"country":55,"countryCode":56,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Herzzentrum Dresden","Dresden","Saxony","01307",{"type":58,"coordinates":85},[86,87],13.73832,51.05089,{"lat":87,"lon":86},[90],{"name":91,"role":39,"phone":22,"phoneExt":22,"email":22},"Norman Mangner, MD",{"facility":93,"status":51,"city":94,"state":82,"zip":95,"country":55,"countryCode":56,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Herzzentrum Leipzig","Leipzig","04289",{"type":58,"coordinates":97},[98,99],12.37129,51.33962,{"lat":99,"lon":98},[102],{"name":103,"role":39,"phone":22,"phoneExt":22,"email":22},"Michael Borger, MD",{"facility":105,"status":106,"city":107,"state":22,"zip":108,"country":55,"countryCode":56,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Deutsches Herzzentrum der Charité Berlin","RECRUITING","Berlin","13353",{"type":58,"coordinates":110},[111,112],13.41053,52.52437,{"lat":112,"lon":111},[115],{"name":37,"role":39,"phone":22,"phoneExt":22,"email":22},{"facility":117,"status":51,"city":118,"state":22,"zip":119,"country":55,"countryCode":56,"cosmosGeoPoint":120,"geoPoint":124,"contacts":125},"Uniklinik Köln","Cologne","50937",{"type":58,"coordinates":121},[122,123],6.95,50.93333,{"lat":123,"lon":122},[126],{"name":127,"role":39,"phone":22,"phoneExt":22,"email":22},"llija Djordjevic, MD",{"facility":129,"status":51,"city":130,"state":22,"zip":131,"country":55,"countryCode":56,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"Westdeutsches Herz- und Gefäßzentrum Essen","Essen","45147",{"type":58,"coordinates":133},[134,135],7.01228,51.45657,{"lat":135,"lon":134},[138],{"name":139,"role":39,"phone":22,"phoneExt":22,"email":22},"Payam Akhyari, MD",{"type":141,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100574895",false,"NCT06765226","Impella Pump Return Study to Analyze Deposits and Biomaterial in Used Pumps","Abiomed Impella Pump Return Registry - Observational Study","Inclusion Criteria:\n\n* Patients with Impella 5.5 therapy and duration of support for ≥ 25 days OR Patients with Impella CP therapy and duration of support for \\> 4 days\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years","ALL","18 Years",{"count":151,"type":152},200,"ESTIMATED","OBSERVATIONAL","Analysis of cell and protein deposits on the Impella Heart Pump.",[156],"Heart Failure","2025-09-30",{"date":159,"type":160},"2025-10-03","ACTUAL",{"date":162,"type":160},"2025-09-21",{"date":164,"type":152},"2031-01-31",{"name":5,"class":6},7]