[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100358486":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":21,"studyPopulation":21,"armGroups":30,"interventions":52,"overallOfficials":21,"centralContacts":68,"locations":74,"responsibleParty":99,"collaborators":21,"id":103,"slug":21,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":21,"eligibilityCriteria":108,"healthyVolunteers":109,"sex":110,"minAge":111,"maxAge":21,"enrollmentInfo":112,"targetDuration":21,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":123,"overallStatus":77,"whyStopped":21,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"University of Texas, El Paso","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":21},[9],{"measure":10,"description":11,"timeFrame":12},"Glycemic Control","Insulin Sensitivity will be measured through repeated blood sampling during an Oral Glucose Tolerance Test and Continuous Glucose Monitoring","8 weeks",[14,18],{"measure":15,"description":16,"timeFrame":17},"Respiratory Exchange Ratio","Respiratory Exchange Ratio will be used to quantify substrate utilization (fats vs carbohydrates) through the use of indirect calorimetry of in vivo gas exchange","8 Weeks",{"measure":19,"description":20,"timeFrame":17},"Amount of lean mass","Amount of lean mass will be measured by dual energy x-ray absortiometry",null,{"allocation":23,"interventionModel":24,"interventionModelDescription":21,"primaryPurpose":25,"observationalModel":21,"timePerspective":21,"maskingInfo":26},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":27,"maskingDescription":21,"whoMasked":28},"SINGLE",[29],"OUTCOMES_ASSESSOR",[31,37,43,48],{"label":32,"type":33,"description":34,"interventionNames":35},"Control","PLACEBO_COMPARATOR","Participants will receive stimulation only up to sensory level.",[36],"Device: Neuromuscular Electrical Stimulation (Sensory)",{"label":38,"type":39,"description":40,"interventionNames":41},"NMES","EXPERIMENTAL","Participants will receive stimulation up to maximum tolerable level.",[42],"Device: Neuromuscular Electrical Stimulation",{"label":44,"type":33,"description":45,"interventionNames":46},"Resistance Training","Participants will receive exercise training with stimulation up to sensory level.",[36,47],"Other: Resistance Training",{"label":49,"type":39,"description":50,"interventionNames":51},"Resistance Training + NMES","Participants will receive exercise training with stimulation up to maximum tolerable intensity.",[42,47],[53,59,65],{"type":54,"name":55,"description":56,"armGroupLabels":57,"otherNames":58},"DEVICE","Neuromuscular Electrical Stimulation (Sensory)","Group will receive Electrical Stimulation up to sensory level",[32,44],[32],{"type":54,"name":60,"description":61,"armGroupLabels":62,"otherNames":63},"Neuromuscular Electrical Stimulation","Group will receive Electrical Stimulation up to maximum tolerable level",[38,49],[64],"NMES Group",{"type":6,"name":44,"description":66,"armGroupLabels":67,"otherNames":21},"Group will receive exercise training.",[44,49],[69],{"name":70,"role":71,"phone":72,"phoneExt":21,"email":73},"Sudip Bajpeyi, PhD","CONTACT","9157475461","sbajpeyi@utep.edu",[75],{"facility":76,"status":77,"city":78,"state":79,"zip":80,"country":81,"countryCode":82,"cosmosGeoPoint":83,"geoPoint":88,"contacts":89},"University of Texas at El Paso","RECRUITING","El Paso","Texas","79968","United States","US",{"type":84,"coordinates":85},"Point",[86,87],-106.48693,31.75872,{"lat":87,"lon":86},[90,92,95,97],{"name":91,"role":71,"phone":72,"phoneExt":21,"email":73},"Sudip R Bajpeyi, PhD",{"name":93,"role":94,"phone":21,"phoneExt":21,"email":21},"Michelle Galvan, B.S.","SUB_INVESTIGATOR",{"name":96,"role":94,"phone":21,"phoneExt":21,"email":21},"Jehu N Apaflo, M.S.",{"name":98,"role":94,"phone":21,"phoneExt":21,"email":21},"Gabriel Narvaez, B.S.",{"type":100,"investigatorFullName":101,"investigatorTitle":102,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"PRINCIPAL_INVESTIGATOR","Sudip Bajpeyi","Associate Professor","100358486",false,"NCT03947697","Improving Glycemic Control With Electrical Stimulation","Improving Glycemic Control With Electrical Stimulation in Mexican-Americans","Inclusion Criteria:\n\n* Overweight\u002FObese (BMI ≥25)\n* Sedentary Lifestyle: Physical Activity Level\\\u003C1.4\n* Less than 150min\u002Fweek of structured Exercise\n\nExclusion Criteria:\n\n* Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications\n* Excessive alcohol, drug abuse, smoking\n* Pregnant Women\n* Unwilling to adhere to the study Intervention",true,"ALL","18 Years",{"count":113,"type":114},60,"ESTIMATED","INTERVENTIONAL",[117],"NA","Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55\u002F15\u002F30% CHO\u002FPRO\u002FFAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min\u002Fday, 3x\u002Fweek) and randomized into placebo\u002Fcontrol, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=15 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.",[120,121,122],"Obesity","Overweight","Insulin Resistance",[120],"2025-02-18",{"date":126,"type":127},"2025-02-20","ACTUAL",{"date":129,"type":127},"2022-08-09",{"date":131,"type":114},"2027-04-30",{"name":5,"class":6},1]