Improving Sleep Health and Circadian Timing to Support Cardiometabolic Health in Adolescents

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-19
SponsorUniversity of Colorado, Denver

About this trial

Many teenagers get too little and late timed sleep. High body weight and diabetes are increasing in teenagers as well. This study plans to learn more about whether improving sleep habits can help improve how the body regulates blood sugar and energy use in teenagers who have higher body weight. To answer this question, the investigators plan to enroll teenagers who get \<7 hours of sleep on school nights and measure changes in blood sugars and energy use after two weeks of typical sleep (sleeping on their normal school schedule) and two weeks of a sleep intervention that includes spending longer time in bed at night, melatonin, and morning light.

Eligibility criteria

Qualifiers

High school students between 14-19 years

Overweight/obesity (BMI >85% for age and sex)

Have habitually insufficient sleep, defined as ≤ 7 hours per night on school days

Habitually inactive (≤ 3 h of physical activity reported per week)

Disqualifiers

Reported diagnosis of sleep disorder (e.g., insomnia, obstructive sleep apnea)

Medical comorbidities that impact sleep or insulin sensitivity (e.g., diabetes [based on history or screening HbA1c])

Regular use of medications affecting sleep or insulin sensitivity (e.g., stimulants, sleep aids, systemic steroids, insulin sensitizers, GLP-1 agonists)

IQ<70 or severe mental illness that may impact sleep or study participation (e.g., schizophrenia), eating disorder, or active suicidal ideation

Trial design

Treatments tested in this trial

  • Circadian/Sleep (C/S)

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

University of Colorado, Denver

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator