[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644879":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":24,"locations":34,"responsibleParty":54,"collaborators":10,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":76,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"South Valley University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"group A: systemic lupus erythrematosus",null,"about 20 patients diagnosed with SLE based on 2019 EULAR\u002FACR.",{"label":13,"type":10,"description":14,"interventionNames":10},"group B:healthy controls","10 with no personal or family history of autoimmune diseases or chronic inflammatory disorders.",[16,20],{"name":17,"affiliation":18,"role":19},"Eisa Mohammed Hegazy, Professor","Dermatology, Venereology & Andrology Department ,Faculty of Medicine ,South Valley University.","STUDY_CHAIR",{"name":21,"affiliation":22,"role":23},"Mohammed Hosny Hassan, Professor","Biochemistry , Qena faculty of medicine ,south valley university.","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Dina Fetouh Abdel-latif, MSc","CONTACT","+201283364643","dedemoona@gmail.com",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Soheir abdel- Hamid Ali, lecturer","+201066877343","Soher.abdel-hamid@med.svu.edu.eg",[35],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"South Valley University Hospital","Qina","Egypt",{"type":40,"coordinates":41},"Point",[42,43],32.72671,26.16418,{"lat":43,"lon":42},[46,50],{"name":47,"role":27,"phone":48,"phoneExt":10,"email":49},"Ebtehal Alaa El-din Kotp, lecturer","+201066798383","Ebtehal-alaa@med.svu.edu.eg",{"name":51,"role":27,"phone":52,"phoneExt":10,"email":53},"Shimaa Saber Ahmed, lecturer","+201006393764","shimaasaber063@gmail.com",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dina Fetouh Abdel Latif","resident","100644879",false,"NCT07675837","Inducible Co-stimulator Gene With Systemic Lupus Erythematosus","Association of ICOS Gene Polymorphism With Susceptibility and Severity of Systemic Lupus Erythematosus.","ICOS\u002FSLE","Inclusion Criteria:\n\n* Patients diagnosed with SLE based on 2019 EULAR\u002FACR Male or female. willing to provide written informed consent for participation and genetic testing\n\nExclusion Criteria:\n\n* Other autoimmune diseases or chronic inflammatory disorders. Malignancy. Pregnancy or breastfeeding. Inability to provide informed consent.",true,"ALL","18 Years","65 Years",{"count":70,"type":71},30,"ESTIMATED","OBSERVATIONAL","The aim of this study is to investigate the association between ICOS gene polymorphism and susceptibility to systemic lupus erythematosus (SLE), as well as its impact on disease severity.",[75],"Systemic Lupus Erthematosus","NOT_YET_RECRUITING","2026-06-23",{"date":79,"type":80},"2026-06-30","ACTUAL",{"date":82,"type":71},"2026-06",{"date":84,"type":71},"2027-07",{"name":5,"class":6},1]