[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637310":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":54,"collaborators":25,"id":58,"slug":25,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":25,"overallStatus":37,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"October 6 University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 (control group)","ACTIVE_COMPARATOR","Patients will receive minimally invasive non-Surgical technique (MINST) alone",[13],"Procedure: Minimally invasive non-Surgical technique",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2 (Test group)","EXPERIMENTAL","Patients will receive minimally invasive non-Surgical technique (MINST)+ injectable platelet-rich fibrin (i-PRF) injection",[19],"Procedure: Minimally invasive non-Surgical technique + platelet-rich fibrin",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Minimally invasive non-Surgical technique",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Minimally invasive non-Surgical technique + platelet-rich fibrin",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Amir R Elngar, B.D.S","CONTACT","00201004634587","amirreda059@gmail.com",[36],{"facility":5,"status":37,"city":38,"state":25,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Cairo","12511","Egypt",{"type":42,"coordinates":43},"Point",[44,45],31.24967,30.06263,{"lat":45,"lon":44},[48,49,52],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":50,"role":51,"phone":25,"phoneExt":25,"email":25},"Reham L Aggour, MD","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":25,"phoneExt":25,"email":25},"Amany A Alaraby, MD",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Amir Reda Ahmed Mohamed Elngar","B.D.S Faculty of Dentistry, October 6 University, Egypt.","100637310",false,"NCT07613606","Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects","Injectable Platelet-Rich Fibrin (i-PRF) With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients of both genders \\>18 years old, medically free of systemic diseases affecting periodontal regeneration.\n* Diagnosis of 'periodontitis' stage III (grades B or C).\n* Single-rooted and multi-rooted vital teeth in either the maxilla or the mandible.\n* Presence of comparable bilateral two- or three-walled intrabony defects \\[probing pocket depth (PPD), \\> 5 mm with intrabony defect depth ≥ 3 mm, from the alveolar crest to the defect base, at screening radiograph\\] not in a furcation-involved tooth.\n\nExclusion Criteria:\n\n* Patients with systemic illness known to affect the outcome of periodontal therapy, including diabetes, immune deficiencies, etc.\n* Pregnant and lactating women\n* Current use of any form of tobacco.\n* Non-surgical periodontal treatment in the past 6 months, or surgical periodontal treatment in the past 12 months.\n* Degree 2 or 3 mobility of the involved sites.6.\n* Presence of periapical pathology, acute infection, or subgingival restoration which could interfere with clinical measurements.","ALL","18 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study aims to clinically and radiographically evaluate the adjunctive effect of injectable platelet-rich fibrin (i-PRF) used in combination with a minimally invasive non-surgical technique for the regenerative treatment of intrabony periodontal defects.",[74,75,76],"Platelet-Rich Fibrin","Minimally Invasive Non-Surgical Technique","Periodontal Intrabony Defects","2026-05-21",{"date":79,"type":80},"2026-05-29","ACTUAL",{"date":82,"type":80},"2026-03-01",{"date":84,"type":68},"2026-12-01",{"name":5,"class":6},1]