[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629348":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":56,"collaborators":10,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":69,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":78,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Reset Medical and Wellness Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ropivacaine Based BCSB",null,"This cohort consists of combat veterans participating in the RESET study to evaluate the effects of bilateral cervical sympathetic ganglion blocks (BCSB) on post-traumatic stress symptoms and suicide risk. Participants receive one procedures as a clinical intervention. Some participants may decided to access additional therapies, making BCSB an integrative model.",[13],"Procedure: stellate ganglion block with 0.5% ropivacaine",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","stellate ganglion block with 0.5% ropivacaine","This study is distinct because it evaluates an integrative, dual-level bilateral cervical sympathetic block (BCSB), a more comprehensive autonomic intervention than the traditional unilateral SGB, specifically in Special Operations Veterans, a uniquely high-trauma, high-TBI population rarely studied. It is also the first to directly compare BCSB alone versus BCSB combined with structured integrative psychological therapy, using a prospective design with validated outcome measures, strict inclusion\u002Fexclusion criteria, and standardized FDA-approved dosing. By incorporating TBI-specific symptom tracking and applying IND-level rigor in a specialized trauma-informed clinical setting, this study fills critical gaps left by prior SGB research and offers a clearer understanding of who benefits most and why.",[9],[21,22,23,24,25,26,27,28,29],"Cervical Sympathetic Block","Dual Level Cervical Sympathetic Block","Dual Level Stellate Ganglion Block","SGB","DCSB","Bilateral Cervical Sympathetic Block","DSGB","ASGB","Advanced Stellate Ganglion Block",[31],{"name":32,"affiliation":5,"role":33},"Michael Louwers, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":10,"email":38},"CONTACT","877-737-3810","mlouwers@theresetcenter.com",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Strongsville","Ohio","44136","United States",{"type":47,"coordinates":48},"Point",[49,50],-81.83569,41.3145,{"lat":50,"lon":49},[53],{"name":54,"role":36,"phone":55,"phoneExt":10,"email":38},"Michael Louwers","8777373810",{"type":33,"investigatorFullName":54,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Medical Director and CEO Reset Medical and Wellness Center","100629348",false,"NCT07473505","Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series","Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series.","Inclusion Criteria:\n\n* 18 years or older\n* PTSD (PCL Score of 33 or greater at baseline screening)\n* Willing and able to provide informed consent and complete study procedures\n* Fluent in English\n* Special Operations Forces Veteran\n\nExclusion Criteria:\n\n* Recent Sympathetic Block: Receipt of any cervical sympathetic block (including stellate ganglion block \\[SGB\\], dual sympathetic ganglion block \\[DSGB\\], or bilateral SGB\u002FBCSB), whether unilateral or bilateral, within the past 6 months.\n* Concurrent interventional clinical trial participation: Currently enrolled in another interventional clinical trial or receiving any experimental treatment targeting PTSD, TBI, or autonomic dysfunction during the study period\n* Acute Psychiatric Instability: Currently experiencing acute psychiatric crisis requiring inpatient care, active suicidal or homicidal intent, or untreated mania, psychosis, or severe dissociation\n* Medical Contraindications to BCSB: Any known anatomical abnormalities, bleeding disorders, allergy to local anesthetics, pregnancy, or comorbidities that represent a contraindication to receiving a cervical sympathetic block, per the treating physician's judgment.\n* Language or communication barriers: Inability to read, speak, or understand English sufficiently to complete informed consent and study assessments\n* Low PTSD Symptom Severity at Baseline: PCL-5 Score \\\u003C 33 at screening, indicating subclinical or minimal PTSD symptoms (Rationale: to ensure measurable clinical benefit and reduce floor effects)","ALL","18 Years",{"count":67,"type":68},75,"ESTIMATED","270 Days","OBSERVATIONAL","This study prospectively evaluates the effects of Integrative Bilateral Cervical Sympathetic Block (BCSB) on trauma-related symptoms in Special Operations Veterans, comparing outcomes in those receiving BCSB alone versus BCSB combined with structured integrative therapy. Using standardized FDA-approved dosing, validated symptom measures, and strict safety criteria, the study aims to determine whether this dual-level autonomic intervention improves PTSD-related and TBI-related symptoms, and whether pairing the procedure with therapy enhances durability and overall clinical benefit.",[73,74,75,76,77],"PTSD","Trauma-related Mental Health Symptoms","Moral Injury","Anxiety","Traumatic Brain Injury",[79,80,73,81,82,83,84,76,75,77,85,86],"Bilateral Cervical Sympathetic Blocks","Stellate Ganglion Block","Combat Veterans","Post Traumatic Stress Disorder","Special Operations Forces Veterans","Trauma Related Symptoms","Integrative Therapy","Mental Health","2026-03-17",{"date":89,"type":90},"2026-03-20","ACTUAL",{"date":89,"type":68},{"date":93,"type":68},"2027-07-01",{"name":5,"class":6},1]