[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100448849":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":119,"collaborators":122,"id":130,"slug":24,"hasResults":131,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":131,"sex":137,"minAge":138,"maxAge":139,"enrollmentInfo":140,"targetDuration":24,"studyType":143,"phases":144,"briefSummary":146,"conditions":147,"keywords":24,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":160},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intensive glycemic targets","EXPERIMENTAL","Participants in this arm will target a fasting blood glucose of \\\u003C90 mg\u002FdL and 1 hour post-prandial blood glucose values \\\u003C120 mg\u002FdL.",[13],"Other: Intensive glycemic targets",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard glycemic targets","ACTIVE_COMPARATOR","Participants in this arm will target a fasting blood glucose of \\\u003C95 mg\u002FdL and 1 hour post-prandial blood glucose values \\\u003C140 mg\u002FdL.",[19],"Other: Standard glycemic targets",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Fasting blood glucose \\\u003C90 mg\u002FdL, 1 hour post-prandial blood glucose \\\u003C120 mg\u002FdL",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Fasting blood glucose \\\u003C95 mg\u002FdL, 1 hour post-prandial blood glucose \\\u003C140 mg\u002FdL",[15],[29],{"name":30,"affiliation":5,"role":31},"Christina Scifres, MD","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Sarah Oswalt","CONTACT","(317)944-7069","seoswalt@iu.edu",[39,57,74,89,104],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"University of Alabama at Birmingham","RECRUITING","Birmingham","Alabama","35294","United States",{"type":47,"coordinates":48},"Point",[49,50],-86.80249,33.52066,{"lat":50,"lon":49},[53,56],{"name":54,"role":35,"phone":24,"phoneExt":24,"email":55},"Ashley Battarbee, MD, MSCR","anbattarbee@uambc.edu",{"name":54,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":5,"status":41,"city":58,"state":59,"zip":60,"country":45,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Indianapolis","Indiana","46202",{"type":47,"coordinates":62},[63,64],-86.15804,39.76838,{"lat":64,"lon":63},[67,70,73],{"name":30,"role":35,"phone":68,"phoneExt":24,"email":69},"(317) 948-4103","cmscifre@iu.edu",{"name":71,"role":35,"phone":72,"phoneExt":24,"email":37},"Sarah Oswalt, RN, BSN","(317) 944-7069",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":75,"status":41,"city":76,"state":77,"zip":78,"country":45,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"University of Oklahoma","Norman","Oklahoma","73019",{"type":47,"coordinates":80},[81,82],-97.43948,35.22257,{"lat":82,"lon":81},[85,88],{"name":86,"role":35,"phone":24,"phoneExt":24,"email":87},"Stephanie Pierce, MD","Stephanie-Pierce@ouhsc.edu",{"name":86,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":90,"status":41,"city":91,"state":92,"zip":93,"country":45,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"University of Pittsburgh","Pittsburgh","Pennsylvania","15260",{"type":47,"coordinates":95},[96,97],-79.99589,40.44062,{"lat":97,"lon":96},[100,103],{"name":101,"role":35,"phone":24,"phoneExt":24,"email":102},"Maisa Feghali, MD","feghalim@mwri.magee.edu",{"name":101,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":105,"status":41,"city":106,"state":107,"zip":108,"country":45,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Women and Infants Hospital of Rhode Island","Providence","Rhode Island","02905",{"type":47,"coordinates":110},[111,112],-71.41283,41.82399,{"lat":112,"lon":111},[115,118],{"name":116,"role":35,"phone":24,"phoneExt":24,"email":117},"Methodius Tuuli, MD, MPH, MBA","MTuuli@Wihri.org",{"name":116,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":31,"investigatorFullName":120,"investigatorTitle":121,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Christina Scifres","Associate Professor",[123,124,125,126,129],{"name":90,"class":6},{"name":40,"class":6},{"name":75,"class":6},{"name":127,"class":128},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH",{"name":105,"class":6},"100448849",false,"NCT05124808","Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes","Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes Mellitus: A Multicenter Randomized Trial","iGDM","Inclusion Criteria:\n\n* Pregnant women between the ages of 18-45\n* Singleton gestation\n* Gestational age between 12 0\u002F7-32 6\u002F7 weeks' gestation with gestational diabetes diagnosed during this time frame using either a 50g 1-hr GCT ≥200 mg\u002FdL or two or more abnormal values on a 100g OGTT using the Carpenter-Coustan Criteria\n* Overweight or obese BMI at the first prenatal visit (BMI ≥25 kg\u002Fm2 or ≥23 kg\u002Fm2 in Asian Americans)\n\nExclusion Criteria:\n\n* Inability or unwillingness to provide informed consent\n* Inability to communicate with members of the study team, despite the presence of an interpreter\n* Planned delivery at a non-study affiliated hospital\n* Known renal disease with a baseline creatinine \\>1.5 mg\u002FdL\n* Significant fetal anomalies diagnosed prior to study enrollment (these will include anomalies such as gastroschisis, spina bifida, complex congenital heart disease, or serious karyotypic anomalies that may lead to early delivery or increased risk of neonatal death)\n* Oral or IV\u002FIM steroid use within 7 days of study enrollment","FEMALE","18 Years","45 Years",{"count":141,"type":142},828,"ESTIMATED","INTERVENTIONAL",[145],"NA","This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.",[148,149,150],"Gestational Diabetes","Pregnancy, High Risk","Overweight and Obesity","2026-06-22",{"date":153,"type":154},"2026-06-24","ACTUAL",{"date":156,"type":154},"2022-03-01",{"date":158,"type":142},"2026-12-31",{"name":5,"class":6},5]