[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607656":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":60,"collaborators":26,"id":64,"slug":26,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"The Second Hospital of Anhui Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"real stimulation","ACTIVE_COMPARATOR","Participants will receive active TIS 10 to 14 times.",[13],"Device: Temporal Interference Stimulation (TIS)",{"label":15,"type":16,"description":17,"interventionNames":18},"sham stimulation","SHAM_COMPARATOR","Participants will receive sham TIS 10 to 14 times.",[19],"Device: Sham temporal interference stimulation (TIS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Temporal Interference Stimulation (TIS)","The total stimulation duration was 30 minutes, including a 30-second current ramp-up at the beginning and a 30-second ramp-down at the end.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham temporal interference stimulation (TIS)","Sham stimulation had only 30 seconds of current ramping-up and ramping-down at the beginning and end of the stimulation, respectively, to simulate the sensation of actual stimulation",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yanghua Tian, PhD","CONTACT","0551 6599 7278","zylykd@163.com",[38,53],{"facility":39,"status":40,"city":41,"state":42,"zip":26,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Anhui Medical University","RECRUITING","Hefei","Anhui","China",{"type":45,"coordinates":46},"Point",[47,48],117.28083,31.86389,{"lat":48,"lon":47},[51],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":52},"ayfytyh@126.com",{"facility":54,"status":40,"city":41,"state":42,"zip":26,"country":43,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"Anhui Mental Health Center",{"type":45,"coordinates":56},[47,48],{"lat":48,"lon":47},[59],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":52},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Yanghua Tian","Vice President of Anhui Medical University","100607656",false,"NCT07191392","Intervention Effect of Temporal Interference Stimulation (TIS) on Depressive Disorder","Inclusion Criteria:\n\n* the patients were diagnosed by more than 2 psychiatrists and met the diagnostic criteria of DSM-5 for depression, and HAMD\\>17, BSS\\>6, PHQ-15\\>5.\n* the age ranged from 18 to 65 years old, and the length of education was more than 5 years.\n* the visual acuity or corrected visual acuity is normal, right-handed, can cooperate with the completion of various experimental tests.\n\nExclusion Criteria:\n\n* accompanied by severe somatic diseases, such as severe heart, liver, renal insufficiency and so on.\n* accompanied by other neurological diseases, such as stroke, epilepsy and so on. pregnant and lactating women.\n* accompanied by other mental disorders, such as drug abuse, schizophrenia, schizophrenic affective",true,"ALL","12 Years","60 Years",{"count":74,"type":75},60,"ESTIMATED","INTERVENTIONAL",[78],"NA","To investigate the effect of Temporal Interference Stimulation (TIS) on associative memory (AM) in patients with depressive disorder",[81,82],"Depressive Disorder","Temporal Interference Stimulation","2026-03-09",{"date":85,"type":86},"2026-03-10","ACTUAL",{"date":88,"type":86},"2025-09-01",{"date":90,"type":75},"2026-06",{"name":5,"class":6},2]