Interventions in Mathematics and Cognitive Skills

ConditionsMath Learning Disability Child Development Developmental Disability Learning Disabilities Learning Disabled Learning Curve Mathematics Disorder Dyscalculia Dyscalculia, Primary Dyscalculia, Acquired Specific Learning Disorder, With Impairment in Mathematics Individuality Behavior, Child Behavior and Behavior Mechanisms Behavior Decision Making Neuronal Plasticity Cognition Cognition Disorder Cognitive Dysfunction Cognitive Change Cognitive Impairment, Mild Cognitive Developmental Delay Cognitive Orientation Cognitive Delay, Mild Cognitive Deficits, Mild Cognitive Abnormality Neuroscience

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age6-12

SponsorStanford University

About this trial

The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

Eligibility criteria

Qualifiers

Elementary school aged children starting from first grade (6-12 years old)

IQ: Participants with a Full Scale IQ > 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).

Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests

Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests

Disqualifiers

History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)

History of trauma involving head injury

Consistent psychiatric medications

Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)

Trial design

Treatments tested in this trial

Interventions in Mathematics and Cognitive Skills - Experimental
Interventions in Mathematics and Cognitive Skills - Active Comparator

Treatment groups

180 Participants

are divided into 2 treatment groups

Locations

Stanford Cognitive and Systems Neuroscience Laboratory94304, Palo AltoCalifornia, United States

Sponsors and collaborators

Stanford University

Lead sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator

Source ClinicalTrials.gov