[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100235534":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":21,"studyPopulation":22,"armGroups":17,"interventions":23,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":63,"collaborators":17,"id":66,"slug":17,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":17,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":17,"maxAge":17,"enrollmentInfo":72,"targetDuration":17,"studyType":75,"phases":17,"briefSummary":76,"conditions":77,"keywords":17,"overallStatus":44,"whyStopped":17,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Medical College of Wisconsin","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"Changes of volumes from baseline of organs at risk during and after radiation therapy.","Changes of organs at risk volumes (cm\\^3) during and after radiation therapy.","2 years",[14],{"measure":15,"description":16,"timeFrame":12},"Changes of volumes from baseline or tumors during and after radiation therapy.","Changes of tumor volumes (cm\\^3) during and after radiation therapy.",null,{"allocation":17,"interventionModel":17,"interventionModelDescription":17,"primaryPurpose":17,"observationalModel":19,"timePerspective":20,"maskingInfo":17},"CASE_CONTROL","PROSPECTIVE","The accurate and detailed knowledge of the changes (e.g., anatomically\u002Fbiologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site\u002Ftype. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic\u002Fbiological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and\u002For improving tumor local control.","Cancer patients who have completed treatment.",[24],{"type":25,"name":26,"description":27,"armGroupLabels":17,"otherNames":17},"RADIATION","Radiation Therapy","Radiation therapy plans for cancer patients who have completed treatment.",[29],{"name":30,"affiliation":5,"role":31},"Eric Paulson, PhD","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":17,"email":37},"Medical College of Wisconsin Cancer Center Clinical Trials Office","CONTACT","414-805-8900","cccto@mcw.edu",{"name":30,"role":35,"phone":39,"phoneExt":17,"email":40},"805-4400","epaulson@mcw.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Froedtert Hospital","RECRUITING","Milwaukee","Wisconsin","53226","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-87.90647,43.0389,{"lat":54,"lon":53},[57,60,62],{"name":30,"role":35,"phone":58,"phoneExt":17,"email":59},"414-805-4400","ali@mcw.edu",{"name":61,"role":35,"phone":17,"phoneExt":17,"email":17},"PhD",{"name":30,"role":31,"phone":17,"phoneExt":17,"email":17},{"type":31,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"Eric Paulson","Associate Professor","100235534",false,"NCT02344121","Intra- and Inter-fraction Changes in Radiation Therapy","Inclusion Criteria:\n\n°Completed radiation therapy\n\nExclusion Criteria:\n\n°Subjects who refuse voluntary participation","ALL",{"count":73,"type":74},500,"ESTIMATED","OBSERVATIONAL","Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.",[78],"Cancer","2026-04-30",{"date":81,"type":82},"2026-05-06","ACTUAL",{"date":84,"type":17},"2015-01",{"date":86,"type":74},"2028-03-20",{"name":5,"class":6},1]