Investigating Pathological Mechanisms in Non-alcoholic Fatty Liver Disease

ConditionNon-Alcoholic Fatty Liver Disease

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorQueen Mary University of London

About this trial

To identify key characteristics of the tissue resident and peripherally circulating immune-phenotype in addition to blood markers, metabolic profile, faecal and oral microbiota in non-alcoholic fatty liver disease

Eligibility criteria

Qualifiers

Age ≥18 years

Confirmed non-alcoholic Fatty liver disease (diagnosed clinically, radiologically or histologically)

If diabetic, Diagnosed with Type 2 Diabetes Mellitus

Disqualifiers

Unwilling or unable to give informed consent

Type 1 Diabetes Mellitus

Other form of liver disease (other than NAFLD)

Taking medication associated with liver dysfunction (except methotrexate)

Trial design

Treatments tested in this trial

Bariatric Surgery

Treatment groups

153 Participants

are divided into 3 treatment groups

Locations

Homerton University Hospital Foundation TrustE9 6SR, LondonGreater London, United Kingdom

Sponsors and collaborators

Queen Mary University of London

Lead sponsor

Homerton University Hospital NHS Foundation Trust

Collaborator

Barts & The London NHS Trust

Collaborator

King's College Hospital NHS Trust

Collaborator

Source ClinicalTrials.gov