Health Trials

About this trial

1. Identifying the association between hyperuricemia and NAFLD can lead to early detection and prevention of liver fibrosis in adult obese patients. 2. Understanding the relationship between hyperuricemia and NAFLD can inform targeted therapy, such as urate-lowering treatment, to potentially slow disease progression.

3 - To examine the relationship between serum uric acid levels and liver fibrosis severity\*: Assessing the correlation between serum uric acid levels and the severity of liver fibrosis in adult obese patients with NAFLD.

4- To identify potential mechanisms underlying the association\*: Exploring the potential mechanisms by which hyperuricemia may contribute to the development and progression of NAFLD and liver fibrosis in adult obese patients.

Eligibility criteria

Qualifiers

Age: Adults (typically 18-65 years old)

Disqualifiers

excessive alcohol consumption ( > 20 gm /day in men and 10 in g /day in women )

Trial design

Treatments tested in this trial

  • *Lab Methods:* 1- Serum Uric Acid levels 2-Liver Function Tests 3- Lipid Profile . 4- Haemoglobin A1c level . 5- Serum glucose level .
  • *Imaging Studies:* 1- Ultrasound 2 - FibroScan
  • Instruments:* 1- *Automated Analyzers*: Used for blood tests, such as serum uric acid and liver function tests.

Treatment groups

111 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Assiut University

Lead sponsor

Source ClinicalTrials.gov