[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554468":3},{"organization":4,"outcomesModule":7,"designInfo":15,"detailedDescription":18,"studyPopulation":19,"armGroups":11,"interventions":11,"overallOfficials":20,"centralContacts":25,"locations":30,"responsibleParty":58,"collaborators":60,"id":64,"slug":11,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":11,"enrollmentInfo":73,"targetDuration":76,"studyType":77,"phases":11,"briefSummary":78,"conditions":79,"keywords":11,"overallStatus":33,"whyStopped":11,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Società Italiana di Allergologia, Asma e Immunologia Clinica","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9,13],{"measure":10,"description":11,"timeFrame":12},"Life Quality as measured by Standardised Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ(S)) (≥12years)",null,"Every year to ten year",{"measure":14,"description":11,"timeFrame":12},"Life Quality as measured by Paediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) For Children 6 - 12 years",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":16,"timePerspective":17,"maskingInfo":11},"COHORT","PROSPECTIVE","Objectives include:\n\n* Evaluate short and long-term real-life effectiveness and safety of AIT overall, in specific patient groups' phenotypes and with specific AIT products.\n* Evaluate the pertinence and differences in suggesting AIT to a patient comparing physician's evaluation in various settings with established international guidelines, describing the factors associated with treatment choices and changing over time, and promoting interoperability, data sharing, and cross-comparison among centers.\n* Describe long-term respiratory allergic disease evolution in patients treated with AIT.\n* Describe the natural history of the patient population with respiratory allergies and identify patient groups describing their illness burden, management patterns, and clinical progression.\n* Promote the creation of accurate, standardized, and efficient processes for diagnosing and treating respiratory allergic diseases, especially with AIT.\n* Assess biomarker data to predict diagnosis, treatment response and long-term disease progression.","RIAIT is a prospective multicenter observational registry of patients suffering from conjunctivitis, rhinitis, and\u002For allergic asthma eligible for and treated with AIT according to EAACI (European Academy of Allergy and Clinical Immunology) Guidelines.",[21],{"name":22,"affiliation":23,"role":24},"Enrico Marco Heffler, MD, PhD","Humanitas Research Hospital IRCCS, Rozzano-Milan","PRINCIPAL_INVESTIGATOR",[26],{"name":22,"role":27,"phone":28,"phoneExt":11,"email":29},"CONTACT","+39 0282241","enrico.heffler@hunimed.eu",[31,47],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Personalized Medicine, Asthma and Allergy - IRCCS Humanitas Research Hospital, Rozzano, Italy","RECRUITING","Rozzano","Milano","20089","Italy","IT",{"type":40,"coordinates":41},"Point",[42,43],9.1559,45.38193,{"lat":43,"lon":42},[46],{"name":22,"role":24,"phone":11,"phoneExt":11,"email":11},{"facility":48,"status":33,"city":49,"state":11,"zip":11,"country":37,"countryCode":38,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"Azienda Ospedaliera Universitaria Istituto di Ricovero e Cura a Carattere Scientifico","Florence",{"type":40,"coordinates":51},[52,53],11.24626,43.77925,{"lat":53,"lon":52},[56],{"name":57,"role":24,"phone":11,"phoneExt":11,"email":11},"Mattia Giovannini, MD",{"type":59,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[61],{"name":62,"class":63},"Società Italiana di Allergologia e Immunologia Pediatrica (SIAIP)","UNKNOWN","100554468",false,"NCT06499480","Italian Registry of Allergen ImmunoTherapy","Italian Registry of Patients With Allergic Disease and Treated With Allergen ImmunoTherapy","RIAIT","Inclusion Criteria:\n\n* Age ≥ 1 year\n* Confirmed diagnosis of allergic rhinoconjunctivitis and\u002For allergic asthma according to EAACI 2019 guidelines.\n* Having been followed by the recruiting center for at least one month: this is considered necessary to establish that the patients are truly affected by allergic respiratory disease and are eligible for allergen-specific immunotherapy; in this period, screening tests are carried out to exclude and\u002For confirm concomitant diseases (comorbidities). In fact, according to the aforementioned EAACI guidelines, a patient can be defined as truly eligible for allergen-specific immunotherapy only after a preliminary phase in which the patient is treated with symptomatic therapy; this observation period allows a correct evaluation of the real adherence and response to therapy, as well as the identification and appropriate treatment of any comorbidity and the possible elimination of aggravating factors.\n* Having received the prescription of any of the available AIT products in Italy, irrespectively of the selected allergens and the administration route and schedule.\n\nExclusion Criteria:\n\nThere will no be exclusion criteria, in order to allow a real-life vision of the characteristics of these patients eligible for or treated with allergen-specific immunotherapy.","ALL","1 Year",{"count":74,"type":75},5000,"ESTIMATED","10 Years","OBSERVATIONAL","RIAIT (Italian Registry of Allergy Immunotherapy) is a multicenter observational study that aims to prospectively collect the most extensive data available on Italian patients using AIT for respiratory allergies (rhinoconjunctivitis and\u002For asthma) in a real-life context, through a network of allergy centers with specific interest and expertise in the management of allergic respiratory patients.",[80],"Allergic Respiratory Disease","2025-03-03",{"date":83,"type":84},"2025-03-06","ACTUAL",{"date":86,"type":84},"2024-05-01",{"date":88,"type":75},"2035-12-31",{"name":5,"class":6},2]