[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100516131":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":33,"studyPopulation":34,"armGroups":29,"interventions":29,"overallOfficials":29,"centralContacts":35,"locations":41,"responsibleParty":58,"collaborators":29,"id":60,"slug":29,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":29,"maxAge":29,"enrollmentInfo":67,"targetDuration":29,"studyType":70,"phases":29,"briefSummary":71,"conditions":72,"keywords":29,"overallStatus":44,"whyStopped":29,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Imagine Institute","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":29},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Epidemiology of juvenile RRP in France by clinical information","age at onset of disease, symptoms, severity score, intensity of disease characterized by need for endoscopies","10 years",{"measure":14,"description":15,"timeFrame":12},"Epidemiology of juvenile PRR in France according to vaccine and adjuvant therapeutic information","Vaccination and adjuvant therapy information",{"measure":17,"description":18,"timeFrame":12},"Epidemiology of juvenile PRR in France by paraclinical information","results of pulmonary imaging, genetic, anatomopathological and immunological tests",[20,23,26],{"measure":21,"description":22,"timeFrame":12},"Define standardized management of juvenile RRP","Correlations between disease progression and frequency of follow-up, as well as treatments implemented (therapeutic or surgical interventions)",{"measure":24,"description":25,"timeFrame":12},"Therapeutic management of RRP","* Frequency of therapeutic surgery\n* Use of adjuvant therapies",{"measure":27,"description":28,"timeFrame":12},"Prevention of RRP","Analysis of national vaccination coverage with a vaccine immunizing against HPV 6 and 11",null,{"allocation":29,"interventionModel":29,"interventionModelDescription":29,"primaryPurpose":29,"observationalModel":31,"timePerspective":32,"maskingInfo":29},"COHORT","PROSPECTIVE","Recurrent respiratory papillomatosis (RRP) is characterized by the recurrent proliferation of multiple polypoid squamous tumors in the respiratory tract, linked to HPV infection. RRP is a rare disease. However, it is the most common benign laryngeal tumor in children.\n\nThere are currently no French national epidemiological data on this disease. The data collected by the reference centers will enable us to gain a better understanding of this pathology in terms of epidemiology, risk factors, genetic susceptibility and clinical manifestations, as well as to significantly study the efficacy of the various existing therapies and preventive measures, in order to establish a clear, standardized and optimal guideline.","All patients with juvenile PRR in France",[36],{"name":37,"role":38,"phone":39,"phoneExt":29,"email":40},"Nicolas LEBOULANGER, MD","CONTACT","0144494682","nicolas.leboulanger@aphp.fr",[42],{"facility":43,"status":44,"city":45,"state":29,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"hôpital Necker Enfants malades","RECRUITING","Paris","75015","France","FR",{"type":50,"coordinates":51},"Point",[52,53],2.3488,48.85341,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":39,"phoneExt":29,"email":40},"Nicolas Leboulanger",{"type":59,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100516131",false,"NCT06000527","Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort \" REPA \")","REPA","Inclusion Criteria:\n\n* Patients with juvenile PRR (disease onset before age 18)\n* Followed in the :\n\n  * The MALO CRMR\n  * One of the MALO network's CCMRs\n  * One of the main correspondent centers\n\nExclusion Criteria:\n\n* Patients objecting to the collection of their personal data\n* Parents of minor patients objecting to the collection of their child's personal data","ALL",{"count":68,"type":69},200,"ESTIMATED","OBSERVATIONAL","Recurrent respiratory papillomatosis (RRP) is a rare disease. However, it is the most common benign laryngeal tumor in children. To date, no epidemiological data are available in France. The aim of this study is to establish the epidemiology of juvenile PPR.",[73],"Juvenile Recurrent Respiratory Papillomatosis","2023-08-17",{"date":76,"type":77},"2023-08-21","ACTUAL",{"date":79,"type":77},"2022-10-01",{"date":81,"type":69},"2032-09-30",{"name":5,"class":6},1]