[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556927":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":59,"collaborators":28,"id":62,"slug":28,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":28,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":28,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":28,"overallStatus":45,"whyStopped":28,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"2J 40hz Laser Energy","EXPERIMENTAL","Patients will under go their Holmium Laser Enucleation procedure with the laser setting: 2J 40hz",[13],"Procedure: HoLEP",{"label":15,"type":10,"description":16,"interventionNames":17},"2J 50hz Laser Energy","Patients will under go their Holmium Laser Enucleation procedure with the laser setting: 2J 50hz",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"2J 60hz Laser Energy","Patients will under go their Holmium Laser Enucleation procedure with the laser setting: 2J 60hz",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","HoLEP","Patients will be randomized to one of the laser energy groups day of surgery.",[9,15,19],null,[30],{"name":31,"affiliation":5,"role":32},"Amy Krambeck, MD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":28,"email":38},"Allaa Fadl-Alla, BS","CONTACT","312-724-3840","allaa.fadlalla@northwestern.edu",{"name":40,"role":36,"phone":37,"phoneExt":28,"email":41},"Alyssa McDonald, MS","alyssa.mcdonald@northwestern.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Northwestern Medicine","RECRUITING","Chicago","Illinois","60611","United States",{"type":51,"coordinates":52},"Point",[53,54],-87.65005,41.85003,{"lat":54,"lon":53},[57],{"name":58,"role":36,"phone":28,"phoneExt":28,"email":28},"Alyssa McDonald",{"type":32,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Amy Krambeck","Urologic Surgeon","100556927",false,"NCT06531473","Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures","Laser Outcomes Associated With HoLEP Procedures","Inclusion Criteria:\n\n* Males 18-89 who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms, that are typically caused by enlarged prostates\n\nExclusion Criteria:\n\n* Prostates measurements over 200g\n* Patients who lack decisional capacity\n* Patients who are non-english speakers","MALE","18 Years","89 Years",{"count":72,"type":73},300,"ESTIMATED","INTERVENTIONAL",[76],"NA","The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate. There is currently no gold-standard laser settings for HoLEP procedures. In the investigator's current high-volume practice, the following settings for enucleation are: 2j 50hz. These settings are conventional settings, but there is no literature to prove optimal laser settings. The investigators hypothesizes that utilization of higher laser settings may be associated with a clinically significant (defined as \\> 10%) decrease in procedural time without any detrimental postoperative outcomes, and a utilization of lower laser settings may be associated with a clinically significant (defined as \\>10%) reduction in postoperative irritative voiding symptoms without any detrimental postoperative outcomes.",[79,80],"Urologic Diseases","Prostate Obstruction","2024-11-12",{"date":83,"type":84},"2024-11-14","ACTUAL",{"date":86,"type":84},"2024-03-04",{"date":88,"type":73},"2026-08-30",{"name":5,"class":6},1]