Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorSeattle Children's Hospital
About this trial
The purpose of this study is to evaluate the use of diode laser photocoagulation of the communicating vessels in twin-to- twin transfusion syndrome (TTTS) with respect to maternal, fetal and neonatal outcomes.
Eligibility criteria
Qualifiers
Single placenta (Monochorionic)
Polyhydramnios present in recipient twin (Greater than 8 cm maximum vertical pocket below 20 weeks and greater than a 10 cm pocket for greater than 20 weeks gestational age)
Oligohydramnios present in donor twin (Less than 2 cm maximum vertical pocket)
Prominent bladder in the recipient/ non-filling bladder in the donor
Disqualifiers
Patients unwilling to participate in the study or to be followed up
Presence of major congenital anomalies incompatible with survival
Active pre-term labor Ruptured membranes
Chorioamnionitis
Trial design
Treatments tested in this trial
- Fetoscopic laser ablation
Treatment groups
2,000 Participants
are divided into 1 treatment groupLocations
2Seattle Childrens Hospital98015, SeattleWashington, United States
University of Washington98195, SeattleWashington, United States
Sponsors and collaborators
Seattle Children's Hospital
Lead sponsor
Source ClinicalTrials.gov