About this trial

The goal of this clinical trial is to learn if laterality training (a type of brain-based therapy) can help reduce pain and change how people with chronic musculoskeletal pain experience and describe their pain. The study will focus on adults with shoulder or knee pain lasting longer than 6 months.

The main questions it aims to answer are:

Does laterality training lead to a reduction in self-reported pain levels?

Does laterality training reduce the area of the body that participants indicate as painful in their pain drawings?

Does laterality training improve accuracy and speed in left/right judgment tasks?

Researchers will compare participants who complete laterality training to those who complete a non-therapeutic cognitive task (a word puzzle) to see if laterality training changes pain drawings and improves pain outcomes.

Participants will:

Complete a pre-intervention assessment including pain ratings, pain drawings, and a left/right judgment test

Be randomly assigned to one of two groups:

Intervention group: Complete 5 one-minute sessions of laterality training using a tablet-based app called Recognise™, identifying left or right hand/foot images depending on the location of their pain

Control group: Complete a 10-minute crossword puzzle activity (non-therapeutic)

Complete the same assessments after the activity (pain ratings, pain drawings, left/right judgment test)

The study will take place at two outpatient physical therapy clinics. Participation involves a single session lasting approximately 30-45 minutes. There is no cost to participate, and no compensation is provided. Participation is voluntary, and all personal data will be kept confidential.

This research will help determine whether laterality training, a non-invasive brain-based technique, can reduce pain and improve quality of life in people with long-standing musculoskeletal pain.

Eligibility criteria

Qualifiers

Adults aged 18 years or older

Diagnosis of chronic shoulder or knee pain lasting more than 6 months

Able to read and understand English

Willing to provide written informed consent

Disqualifiers

Visual impairments that would interfere with laterality training (e.g., blindness or significant difficulty with vision)

Previous participation in laterality (left/right discrimination) training

Unwilling or unable to participate in the study procedures

Trial design

Treatments tested in this trial

  • Laterality Training
  • Sham (No Treatment)

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

2
Rock Valley Physical Therapy61265, MolineIllinois, United States
Rock Valley Physical Therapy52039, DavenportIowa, United States

Sponsors and collaborators

Hawaii Pacific University

Lead sponsor

Therapeutic Neuroscience Research Group

Collaborator