[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100400216":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":16,"studyPopulation":17,"armGroups":18,"interventions":11,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":61,"collaborators":11,"id":64,"slug":11,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":11,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":44,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Leipzig","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Gene-dependent association with phenotypical traits in overweight and obese children",null,"20 years",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":14,"timePerspective":15,"maskingInfo":11},"COHORT","CROSS_SECTIONAL","In order to identify single nucleotide polymorphisms blood and serum samples during oral glucose tolerance testing are routinely obtained from pediatric patients visiting the adiposity outpatient clinic.","Overweight and obese children and adolescents",[19,22,25],{"label":20,"type":11,"description":21,"interventionNames":11},"Children with overweight and obesity","Overweight and obese children and adolescents visiting the adiposity outpatient clinic.",{"label":23,"type":11,"description":24,"interventionNames":11},"adults","follow up of patients into adulthood",{"label":26,"type":11,"description":27,"interventionNames":11},"control group","matched control group with children, adolescents and aduts without obesity",[29],{"name":30,"affiliation":5,"role":31},"Antje Körner, Prof, MD","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":11,"email":36},"CONTACT","+49 341 97-26500","Antje.Koerner@medizin.uni-leipzig.de",{"name":38,"role":34,"phone":39,"phoneExt":11,"email":40},"Robert Stein, MD","+49 341 97-26537","robert.stein@medizin.uni-leipzig.de",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"University Leipzig Medical Center, Department of Women and Child Health, Center for Pediatric Research Leipzig","RECRUITING","Leipzig","Saxony","04103","Germany","DE",{"type":51,"coordinates":52},"Point",[53,54],12.37129,51.33962,{"lat":54,"lon":53},[57,58],{"name":30,"role":34,"phone":35,"phoneExt":11,"email":36},{"name":59,"role":34,"phone":39,"phoneExt":11,"email":60},"Julian Schwartze","JulianTristan.Schwartze@medizin.uni-leipzig.de",{"type":31,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Antje Koerner, Prof. Dr. med.","Prof. Dr. med.","100400216",false,"NCT04491344","Leipzig Childhood Obesity Study","Extended Geno- and Phenotyping of Overweight and Obese Children and Adolescents","Inclusion Criteria:\n\n* all pediatric patients seen in the adiposity outpatient clinic\n* informed patient consent\n\nExclusion Criteria:\n\n* none",true,"ALL","1 Month","18 Years",{"count":75,"type":76},3000,"ESTIMATED","OBSERVATIONAL","The aim of this study is to identify polymorphisms that make children and adolescents more prone to obesity and metabolic dysfunction, as well as to identify biomarkers that are linked to causes and consequences of obesity.",[80],"Childhood Obesity",[82,83,84,85,86],"Single nucleotide polymorphisms","Obesity","Insulin resistance","Metabolic syndrome","Oral glucose tolerance test","2023-11-03",{"date":89,"type":90},"2023-11-07","ACTUAL",{"date":92,"type":11},"2002-01",{"date":94,"type":76},"2030-01",{"name":5,"class":6},1]