Lifestyle Intervention In CKD
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDuke University
About this trial
This research study will test whether a 12-week healthy lifestyle program offered through a cardiac rehabilitation center can help lower blood pressure and improve kidney health in adults with advanced chronic kidney disease. Participants will be randomly assigned to either routine kidney health education or take part in a program that includes healthy eating guidance, supervised exercise sessions, and wellness coaching. The goal of the study is to determine whether this program can improve blood pressure and other factors linked to worsening kidney disease.
Eligibility criteria
Qualifiers
Black race; ≥18 years old
history of hypertension
SBP ≥120 or DBP ≥80 mm Hg average of three measurements at screening visit (per KDIGO recommended SBP target of <120 mm Hg)48
Stable anti-hypertensive medication regimen (i.e., no medication changes 4 weeks prior to enrollment);
Disqualifiers
currently receiving or needing dialysis; having received or needing a kidney transplant
acute kidney injury at time of screening
average SBP ≥ 180 mm Hg or DBP ≥ 110 mm Hg at screening
Exaggerated systolic response during ETT (e.g., SBP >210 mmHg in men or >190 mmHg in women)
Trial design
Treatments tested in this trial
- Multi-component lifestyle intervention
- Usual Care Control
Treatment groups
152 Participants
are divided into 2 treatment groupsLocations
This trial has no locations
Sponsors and collaborators
Duke University
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov