Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

ConditionsSleep Phototherapy Glymphatic System Mitochondrial Dynamics Brain Injuries, Traumatic Inflammation

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-89

SponsorOregon Health and Science University

About this trial

This is a clinical trial designed to examine how improved sleep through morning bright light therapy is improving downstream key physiologic processes related to brain health, i.e., mitochondrial function, systemic inflammation, and glymphatic function. All proposed methodology is already approved in other IRB applications.

Eligibility criteria

Qualifiers

Male and female; any race; 18-89 years of age.

Be English speaking.*

Be accessible via phone.

Be non-decisionally impaired. Determined by assessing the subject's ability to verbalize their understanding of the protocol back to us during the informed consent process.

Disqualifiers

None

Trial design

Treatments tested in this trial

Morning Bright Light Therapy
Negative Ion Generator Therapy

Treatment groups

300 Participants

are divided into 2 treatment groups

Locations

Oregon Health and Science University97239, PortlandOregon, United States

Sponsors and collaborators

Oregon Health and Science University

Lead sponsor

Source ClinicalTrials.gov