[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510193":3},{"organization":4,"outcomesModule":7,"designInfo":61,"detailedDescription":68,"studyPopulation":64,"armGroups":69,"interventions":82,"overallOfficials":92,"centralContacts":97,"locations":102,"responsibleParty":461,"collaborators":64,"id":464,"slug":64,"hasResults":465,"nctId":466,"briefTitle":467,"officialTitle":468,"acronym":64,"eligibilityCriteria":469,"healthyVolunteers":465,"sex":470,"minAge":471,"maxAge":472,"enrollmentInfo":473,"targetDuration":64,"studyType":476,"phases":477,"briefSummary":479,"conditions":480,"keywords":483,"overallStatus":105,"whyStopped":64,"lastUpdateSubmitDate":488,"lastUpdatePostDateStruct":489,"startDateStruct":492,"completionDateStruct":494,"leadSponsor":496,"locationsCount":497},{"fullName":5,"class":6},"Zhejiang University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":35},[9],{"measure":10,"description":11,"timeFrame":12},"3-year disease free survival","the time from enrollment until disease relapse or death from any cause 3 years after surgery","3 years",[14,18,22,26,29,32],{"measure":15,"description":16,"timeFrame":17},"Perioperative complications","Complications occurring within 30 days after surgery. Perioperative complications are classified according to the Clavien-Dindo classification system and include intraoperative, short-term, and long-term postoperative complications. The following events are considered serious perioperative complications: hemorrhage requiring transfusion of \\>4 units of packed red blood cells; postoperative complications necessitating emergent surgical intervention; severe infection (as defined by the American College of Chest Physicians\u002FSociety of Critical Care Medicine 1992 criteria); and deaths attributable to the surgical procedure. These should be reported within 30 days postoperatively.","up to 30 days after surgery",{"measure":19,"description":20,"timeFrame":21},"Quality of the specimen","The data included specimen quality, positive margin rate, number of harvested lymph nodes and positive lymph nodes","up to 2 weeks after surgery",{"measure":23,"description":24,"timeFrame":25},"Incidence rates of polyps and adenomas","the incidence rates of polyps and adenomas as seen on colonoscopy at 1, 3 and 5 years after surgery respectively.","5 years",{"measure":27,"description":28,"timeFrame":12},"Scores of quality of life","measured by scores from the Gastrointestinal Symptom Rating Scale (GSRS) at 1, 2, and 3 years after surgery respectively, and scores from the EQ-5D-5L Quality of Life Scale at 1, 2, and 3 years after surgery respectively.",{"measure":30,"description":31,"timeFrame":12},"Scores from the EQ-5D-5L Quality of Life Scale","scores from the EQ-5D-5L Quality of Life Scale at 1, 2, and 3 years after surgery respectively.",{"measure":33,"description":34,"timeFrame":25},"5-year overall survival rate (OS)","The proportion of patients who survived 5 years after surgery, taking into account any cause of death.",[36,40,43,47,51,55,58],{"measure":37,"description":38,"timeFrame":39},"Conversion Rate from Laparoscopic to Open Surgery","The proportion of laparoscopic surgeries that are converted to open surgeries due to intraoperative complications, technical challenges, or other clinical reasons.","Intraoperative period",{"measure":41,"description":42,"timeFrame":39},"LISH Surgery Completion Rate","The proportion of patients in whom the LISH procedure is successfully completed without conversion to TRH or other alternative surgical approaches.",{"measure":44,"description":45,"timeFrame":46},"Minimal Residual Disease (MRD) via Circulating Tumor DNA (ctDNA)","Detection of MRD using circulating tumor DNA (ctDNA) as a biomarker.","Preoperative (7 days), postoperative (7 days), and 3 months post-surgery",{"measure":48,"description":49,"timeFrame":50},"Short- and Long-Term Changes in Gut Microecology","Analysis of gut microbiota, epithelial cells, stromal cells, immune cells, and metabolic products using fecal samples and intestinal biopsy tissues.","Preoperative, postoperative 3 months, 6 months and 12 months",{"measure":52,"description":53,"timeFrame":54},"Glycemic Metabolic Indicators - Hemoglobin A1c (HbA1c)","Measurement of glycated hemoglobin (HbA1c) levels to assess long-term glycemic control.","Preoperative, 3 months, 6 months, and 12 months post-surgery",{"measure":56,"description":57,"timeFrame":54},"Oral Glucose Tolerance Test (OGTT)","Evaluation of glucose metabolism by measuring blood glucose and insulin levels at 0, 30, 60, 120 minutes after oral glucose administration.",{"measure":59,"description":60,"timeFrame":54},"Insulin Resistance (HOMA-IR)","Calculation of insulin sensitivity using fasting glucose and insulin levels",{"allocation":62,"interventionModel":63,"interventionModelDescription":64,"primaryPurpose":65,"observationalModel":64,"timePerspective":64,"maskingInfo":66},"RANDOMIZED","PARALLEL",null,"TREATMENT",{"masking":67,"maskingDescription":64,"whoMasked":64},"NONE","This study is a prospective, multicenter, open-labeled, randomized controlled clinical trial. The enrolled patients will be randomly assigned to either the LISH or TRH group in a 1:1 ratio and will receive the corresponding surgery. The primary endpoint: 3-year disease free survival. The second endpoint: 30-day perioperative complications, pathological outcomes (specimen quality, positive resection margin rate, number of lymph nodes retrieved, and lymph node positivity rate), histological prognostic indicators (planned for superiority testing: 1-, 3-, and 5-year rates of newly detected polyps and adenomas on colonoscopy), quality of life (planned for superiority testing: Gastrointestinal Symptom Rating Scale \\[GSRS\\] score and EQ-5D-5L score), and 5-year overall survival (OS).",[70,76],{"label":71,"type":72,"description":73,"interventionNames":74},"LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）group","EXPERIMENTAL","In LISH group, patients suffering from cancer of the hepatic flexure and proximal transverse colon will be undergoing a novel radical right hemicolectomy technique that allows for the preservation of the ileocecal region.",[75],"Procedure: LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）",{"label":77,"type":78,"description":79,"interventionNames":80},"TRH （Traditional Right Hemicolectomy）group","ACTIVE_COMPARATOR","In TRH group, patients suffering from cancer of the hepatic flexure and proximal transverse colon will be undergoing the traditional radical right hemicolectomy.",[81],"Procedure: TRH（Traditional Laparoscopic Right Hemicolectomy）",[83,88],{"type":84,"name":85,"description":86,"armGroupLabels":87,"otherNames":64},"PROCEDURE","LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）","Preserve the ileocolic blood vessels, and perform dissection of lymph node groups 203, 202, and 201d along the root of ICV(Ileocolic artery)\u002FICA(Ileocolic vein). Group 201d lymph nodes are defined as the distal lymph nodes of the ileocolic vessels (colonic branch). Use an intracavitary cutting and sealing device to transect the proximal colon along the predetermined margin, and transect the transverse colon at 10cm distal to the tumor. Perform ileocecal-transverse colonic anastomosis.",[71],{"type":84,"name":89,"description":90,"armGroupLabels":91,"otherNames":64},"TRH（Traditional Laparoscopic Right Hemicolectomy）","Transect the root of the ileocolic vessels and perform dissection of lymph node groups 203, 202, and 201; sever the roots of the right colic and middle colic vessels, and clear the surrounding lymphoadipose tissue (lymph node groups 211\u002F212\u002F213 and 221\u002F222\u002F223). Transect the transverse colon 10cm distal to the tumor and cut the terminal ileum 10cm from the ileocecal junction. Perform ileum-to-transverse colon anastomosis.",[77],[93],{"name":94,"affiliation":95,"role":96},"Kefeng Ding, PhD","Second Affiliated Hospital, School of Medicine, Zhejiang University","PRINCIPAL_INVESTIGATOR",[98],{"name":94,"role":99,"phone":100,"phoneExt":64,"email":101},"CONTACT","86-571-87784720","dingkefeng@zju.edu.cn",[103,120,137,146,159,172,187,197,206,219,228,241,256,269,278,291,304,316,331,343,352,362,375,387,400,419,428,437,449],{"facility":104,"status":105,"city":106,"state":107,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":110,"geoPoint":115,"contacts":116},"the First Affiliated Hospital of Bengbu Medical Collage","RECRUITING","Bengbu","Anhui","China","CN",{"type":111,"coordinates":112},"Point",[113,114],117.36083,32.94083,{"lat":114,"lon":113},[117,119],{"name":118,"role":99,"phone":64,"phoneExt":64,"email":64},"Muling Liu, phD",{"name":118,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":121,"status":105,"city":122,"state":123,"zip":124,"country":108,"countryCode":109,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"Beijing Cancer Hospital","Beijing","Beijing Municipality","100000",{"type":111,"coordinates":126},[127,128],116.39723,39.9075,{"lat":128,"lon":127},[131,133,135,136],{"name":132,"role":99,"phone":64,"phoneExt":64,"email":64},"Aiwen Wu, PhD",{"name":134,"role":99,"phone":64,"phoneExt":64,"email":64},"Xiangqian Su, PhD",{"name":132,"role":96,"phone":64,"phoneExt":64,"email":64},{"name":134,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":138,"status":105,"city":122,"state":123,"zip":124,"country":108,"countryCode":109,"cosmosGeoPoint":139,"geoPoint":141,"contacts":142},"Peking Union Medical College Hospital",{"type":111,"coordinates":140},[127,128],{"lat":128,"lon":127},[143,145],{"name":144,"role":99,"phone":64,"phoneExt":64,"email":64},"Yi Xiao, PhD",{"name":144,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":147,"status":105,"city":122,"state":123,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":148,"geoPoint":150,"contacts":151},"Cancer Hospital Academy of medicine Scenice",{"type":111,"coordinates":149},[127,128],{"lat":128,"lon":127},[152,154,156,157],{"name":153,"role":99,"phone":64,"phoneExt":64,"email":64},"Qian Liu, phD",{"name":155,"role":99,"phone":64,"phoneExt":64,"email":64},"Xishan Wang",{"name":153,"role":96,"phone":64,"phoneExt":64,"email":64},{"name":158,"role":96,"phone":64,"phoneExt":64,"email":64},"Xishan Wang, phD",{"facility":160,"status":105,"city":161,"state":162,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"the First Affiliated Hospital of Chongqing Medical Collage","Chongqing","Chongqing Municipality",{"type":111,"coordinates":164},[165,166],106.55771,29.56026,{"lat":166,"lon":165},[169,171],{"name":170,"role":99,"phone":64,"phoneExt":64,"email":64},"Zhengqiang Wei, phD",{"name":170,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":173,"status":105,"city":174,"state":175,"zip":176,"country":108,"countryCode":109,"cosmosGeoPoint":177,"geoPoint":181,"contacts":182},"Fujian Cancer Hospital","Fuzhou","Fujian","350001",{"type":111,"coordinates":178},[179,180],119.30611,26.06139,{"lat":180,"lon":179},[183,185],{"name":184,"role":99,"phone":64,"phoneExt":64,"email":64},"Chunkang Yang, PhD",{"name":186,"role":96,"phone":64,"phoneExt":64,"email":64},"Chunkang Yang, MD",{"facility":188,"status":105,"city":174,"state":175,"zip":176,"country":108,"countryCode":109,"cosmosGeoPoint":189,"geoPoint":191,"contacts":192},"Fujian Hospital Medical Union University",{"type":111,"coordinates":190},[179,180],{"lat":180,"lon":179},[193,195],{"name":194,"role":99,"phone":64,"phoneExt":64,"email":64},"Pan Chi",{"name":196,"role":96,"phone":64,"phoneExt":64,"email":64},"Pan Chi, M.D.",{"facility":198,"status":199,"city":200,"state":175,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":201,"geoPoint":205,"contacts":64},"The First Affiliated Hospital of Xiamen University","NOT_YET_RECRUITING","Xiamen",{"type":111,"coordinates":202},[203,204],118.08187,24.47979,{"lat":204,"lon":203},{"facility":207,"status":105,"city":208,"state":209,"zip":210,"country":108,"countryCode":109,"cosmosGeoPoint":211,"geoPoint":215,"contacts":216},"Guangdong Second Provincial General Hospital","Guangzhou","Guangdong","510317",{"type":111,"coordinates":212},[213,214],113.25,23.11667,{"lat":214,"lon":213},[217],{"name":218,"role":99,"phone":64,"phoneExt":64,"email":64},"Han Fanghai, Prof.",{"facility":220,"status":105,"city":208,"state":209,"zip":221,"country":108,"countryCode":109,"cosmosGeoPoint":222,"geoPoint":224,"contacts":225},"The Sixth Affiliated Hospital of Sun Yat-sen University","510655",{"type":111,"coordinates":223},[213,214],{"lat":214,"lon":213},[226],{"name":227,"role":99,"phone":64,"phoneExt":64,"email":64},"Wu Xiaojian",{"facility":229,"status":105,"city":230,"state":231,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":232,"geoPoint":236,"contacts":237},"Union Hospital, Tongji Medical College, Huazhong University of Science and Technolog","Wuhan","Hubei",{"type":111,"coordinates":233},[234,235],114.26667,30.58333,{"lat":235,"lon":234},[238,240],{"name":239,"role":99,"phone":64,"phoneExt":64,"email":64},"Kaixiong Tao, phD",{"name":239,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":242,"status":105,"city":243,"state":244,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":245,"geoPoint":249,"contacts":250},"People's Hospital of Hunan Province","Changsha","Hunan",{"type":111,"coordinates":246},[247,248],112.97087,28.19874,{"lat":248,"lon":247},[251,253,255],{"name":252,"role":99,"phone":64,"phoneExt":64,"email":64},"Zhigang Xiao, phD",{"name":254,"role":99,"phone":64,"phoneExt":64,"email":64},"Zhongcheng Huang, phD",{"name":252,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":257,"status":199,"city":258,"state":259,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":260,"geoPoint":264,"contacts":265},"Jiangsu province hospital","Nanjing","Jiangsu",{"type":111,"coordinates":261},[262,263],118.77778,32.06167,{"lat":263,"lon":262},[266,268],{"name":267,"role":99,"phone":64,"phoneExt":64,"email":64},"Yueming Sun, phD",{"name":267,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":270,"status":105,"city":258,"state":259,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":271,"geoPoint":273,"contacts":274},"Nanjing Drum Tower Hospital",{"type":111,"coordinates":272},[262,263],{"lat":263,"lon":262},[275,277],{"name":276,"role":99,"phone":64,"phoneExt":64,"email":64},"Gang Chen, phD",{"name":276,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":279,"status":105,"city":280,"state":281,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":282,"geoPoint":286,"contacts":287},"The Second Affiliated Hospital of Nanchang University","Nanchang","Jiangxi",{"type":111,"coordinates":283},[284,285],115.85306,28.68396,{"lat":285,"lon":284},[288,290],{"name":289,"role":99,"phone":64,"phoneExt":64,"email":64},"Shengxun Mao, phD",{"name":289,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":292,"status":105,"city":293,"state":294,"zip":295,"country":108,"countryCode":109,"cosmosGeoPoint":296,"geoPoint":300,"contacts":301},"Shandong Cancer Hospital","Jinan","Shandong","250117",{"type":111,"coordinates":297},[298,299],116.99722,36.66833,{"lat":299,"lon":298},[302],{"name":303,"role":99,"phone":64,"phoneExt":64,"email":64},"Sun Yanlai, Prof.",{"facility":305,"status":105,"city":306,"state":294,"zip":307,"country":108,"countryCode":109,"cosmosGeoPoint":308,"geoPoint":312,"contacts":313},"The Affiliated Hospital of Qingdao University","Qingdao","266003",{"type":111,"coordinates":309},[310,311],120.38042,36.06488,{"lat":311,"lon":310},[314],{"name":315,"role":99,"phone":64,"phoneExt":64,"email":64},"Zhou Yanbin, Prof.",{"facility":317,"status":105,"city":318,"state":319,"zip":320,"country":108,"countryCode":109,"cosmosGeoPoint":321,"geoPoint":325,"contacts":326},"Changhai Hospital of Shanghai","Shanghai","Shanghai Municipality","200433",{"type":111,"coordinates":322},[323,324],121.45806,31.22222,{"lat":324,"lon":323},[327,329],{"name":328,"role":99,"phone":64,"phoneExt":64,"email":64},"Wei Zhang",{"name":330,"role":96,"phone":64,"phoneExt":64,"email":64},"Wei Zhang, MD",{"facility":332,"status":105,"city":318,"state":319,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":333,"geoPoint":335,"contacts":336},"Fudan University Shanghai Cancer Center",{"type":111,"coordinates":334},[323,324],{"lat":324,"lon":323},[337,339,341,342],{"name":338,"role":99,"phone":64,"phoneExt":64,"email":64},"Ye Xu, phD",{"name":340,"role":99,"phone":64,"phoneExt":64,"email":64},"Xinxiang Li, phD",{"name":338,"role":96,"phone":64,"phoneExt":64,"email":64},{"name":340,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":344,"status":105,"city":318,"state":319,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":345,"geoPoint":347,"contacts":348},"Ruijin Hospital Affiliated of The Shanghai Jiao Tong University Medical School",{"type":111,"coordinates":346},[323,324],{"lat":324,"lon":323},[349,351],{"name":350,"role":99,"phone":64,"phoneExt":64,"email":64},"Bo Feng, phD",{"name":350,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":353,"status":105,"city":354,"state":355,"zip":356,"country":108,"countryCode":109,"cosmosGeoPoint":357,"geoPoint":361,"contacts":64},"The first affiliated hospital of xi'an jiaotong university","Xi’an","Shanxi","710000",{"type":111,"coordinates":358},[359,360],113.52486,35.99785,{"lat":360,"lon":359},{"facility":363,"status":105,"city":364,"state":365,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":366,"geoPoint":370,"contacts":371},"West China Hospital of Sichuang University","Chengdu","Sichuan",{"type":111,"coordinates":367},[368,369],104.06667,30.66667,{"lat":369,"lon":368},[372,374],{"name":373,"role":99,"phone":64,"phoneExt":64,"email":64},"Ziqiang Wang, phD",{"name":373,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":376,"status":105,"city":377,"state":377,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":378,"geoPoint":382,"contacts":383},"The Cancer Hospital Affiliated of The Xingjiang University Medical School","Xinjiang",{"type":111,"coordinates":379},[380,381],110.38311,40.91904,{"lat":381,"lon":380},[384,386],{"name":385,"role":99,"phone":64,"phoneExt":64,"email":64},"Haijiang Wang, phD",{"name":385,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":388,"status":105,"city":389,"state":390,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":391,"geoPoint":395,"contacts":396},"Yunnan Cancer Hospital","Kunming","Yunnan",{"type":111,"coordinates":392},[393,394],102.71833,25.03889,{"lat":394,"lon":393},[397,399],{"name":398,"role":99,"phone":64,"phoneExt":64,"email":64},"Yunfeng Li, phD",{"name":398,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":401,"status":105,"city":402,"state":403,"zip":404,"country":108,"countryCode":109,"cosmosGeoPoint":405,"geoPoint":409,"contacts":410},"Second Affiliated Hospital Zhejiang University College of Medicine","Hangzhou","Zhejiang","310999",{"type":111,"coordinates":406},[407,408],120.16142,30.29365,{"lat":408,"lon":407},[411,414,418],{"name":412,"role":99,"phone":413,"phoneExt":64,"email":101},"Ke-Feng Ding, phD\u002FMD","86-571-87784827",{"name":415,"role":99,"phone":416,"phoneExt":64,"email":417},"Jian Wang, phD\u002FMD","0571-87784720","wangjian519@zju.edu.cn",{"name":412,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":420,"status":105,"city":402,"state":403,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":421,"geoPoint":423,"contacts":424},"Sir Run Run Shaw Hospital, Zhejiang University School of medicien",{"type":111,"coordinates":422},[407,408],{"lat":408,"lon":407},[425,427],{"name":426,"role":99,"phone":64,"phoneExt":64,"email":64},"Xuefeng Huang, phD",{"name":426,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":429,"status":199,"city":402,"state":403,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":430,"geoPoint":432,"contacts":433},"Zhejiang Cancer Hospital",{"type":111,"coordinates":431},[407,408],{"lat":408,"lon":407},[434,436],{"name":435,"role":99,"phone":64,"phoneExt":64,"email":64},"Haixing Ju, phD",{"name":435,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":438,"status":105,"city":439,"state":403,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":440,"geoPoint":444,"contacts":445},"Jinhua Municipal Central Hospital","Jinhua",{"type":111,"coordinates":441},[442,443],119.64421,29.10678,{"lat":443,"lon":442},[446,448],{"name":447,"role":99,"phone":64,"phoneExt":64,"email":64},"Jinlin Du, phD",{"name":447,"role":96,"phone":64,"phoneExt":64,"email":64},{"facility":450,"status":105,"city":451,"state":403,"zip":64,"country":108,"countryCode":109,"cosmosGeoPoint":452,"geoPoint":456,"contacts":457},"Ningbo No.2 Hospital","Ningbo",{"type":111,"coordinates":453},[454,455],121.54945,29.87819,{"lat":455,"lon":454},[458,460],{"name":459,"role":99,"phone":64,"phoneExt":64,"email":64},"Xiaoyu Dai, phD",{"name":459,"role":96,"phone":64,"phoneExt":64,"email":64},{"type":96,"investigatorFullName":462,"investigatorTitle":463,"investigatorAffiliation":5,"oldNameTitle":64,"oldOrganization":64},"Ding Ke-Feng","Professor","100510193",false,"NCT05923255","LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer","Laparoscopic Ileocecal-Sparing Right Hemicolectomy for Cancer of the Hepatic Flexure and Proximal Transverse Colon -- A Prospective, Multicenter Randomized Control Clinical Trial","Inclusion Criteria:\n\n1. Age between 18-75 years old\n2. ASA classification ≤III\n3. Colon adenocarcinoma confirmed by endoscopy and pathological biopsy\n4. Enhanced abdominal CT indicating the primary lesion is located in the hepatic flexure of the colon or proximal transverse colon (proximal 1\u002F3 of the transverse colon)\n5. Preoperative clinical staging: TanyNanyM0\n6. Patients able to understand the study protocol, willing to participate in the research, and providing written informed consent\n\nExclusion Criteria:\n\n1. Preoperative examination indicates synchronous multiple primary colorectal cancers or other diseases requiring bowel segment resection\n2. Preoperative imaging or intraoperative exploration reveals: 1) tumor involving surrounding organs requiring combined organ resection; 2) presence of distant metastasis; 3) inability to perform R0 resection; 4) fused and fixed lymph nodes at the root of the ileocolic vessels\n3. Additional radical surgery following Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD) procedures\n4. History of any other malignant tumor within the last 5 years or familial adenomatous polyposis, except for cured in situ cervical cancer, basal cell carcinoma, papillary thyroid carcinoma, or skin squamous cell carcinoma\n5. Presence of bowel obstruction, bowel perforation, or intestinal bleeding requiring emergency surgery\n6. Patients unsuitable for or unable to tolerate laparoscopic surgery\n7. Pregnant or lactating women\n8. Patients with a history of psychiatric disorders\n9. Patients who have received neoadjuvant therapy prior to surgery\n10. Patients deemed unsuitable for the study by MDT discussion\n11. Patients unable to understand the study's conditions and objectives, and refusing to sign informed consent.","ALL","18 Years","75 Years",{"count":474,"type":475},568,"ESTIMATED","INTERVENTIONAL",[478],"NA","The goal of this clinical trial is to compare the long-term outcomes of Laparoscopic Ileocecal-Sparing Right Hemicolectomy(LISH) compared to traditional laparoscopic right hemicolectomy(TRH) in the treatment of hepatic flexure colon cancer and proximal transverse colon cancer.",[481,482],"Hepatic Flexure Colon Cancer","Proximal Transverse Colon Cancer",[484,485,486,487],"hepatic flexure colon cancer","proximal transverse colon cancer","ileocecus-sparing","laparoscopic right hemicolectomy","2026-01-25",{"date":490,"type":491},"2026-01-27","ACTUAL",{"date":493,"type":491},"2023-05-14",{"date":495,"type":475},"2031-05-14",{"name":5,"class":6},29]