[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628822":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":40,"locations":46,"responsibleParty":59,"collaborators":63,"id":65,"slug":11,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":11,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":49,"whyStopped":11,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-level laser therapy group","EXPERIMENTAL",null,[13],"Procedure: Low Level Laser Therapy",{"label":15,"type":10,"description":11,"interventionNames":16},"Piezocision group",[17],"Procedure: Piezocision",{"label":19,"type":20,"description":11,"interventionNames":11},"Control group","NO_INTERVENTION",[22,29],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"PROCEDURE","Low Level Laser Therapy","On both right and left sides, LLLT will be performed at the beginning of canine retraction, after 3, 7, 14 days, and then every 14 days for a total four-month period.",[9],[28],"LLLT",{"type":23,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Piezocision","On both right and left sides, a minimally invasive flapless piezocision procedure will be performed each month from the beginning of the canine retraction for a total four-month period.",[15],[34],"Piezosurgery",[36],{"name":37,"affiliation":38,"role":39},"Farouk A Hussein, Professor","Professor in Orthodontics; Faculty of Dental Medicine, Boys, Cairo; Al-Azhar University","STUDY_CHAIR",[41],{"name":42,"role":43,"phone":44,"phoneExt":11,"email":45},"Hesham N Al-Qamhawy","CONTACT","00201099767929","heshamnabil96@gmail.com",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":11,"country":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":11},"Outpatient Clinics of the Department of Orthodontics, Faculty of Dental Medicine, Boys, Cairo, Al-Azhar University.","RECRUITING","Cairo","Cairo Governorate","Egypt",{"type":54,"coordinates":55},"Point",[56,57],31.24967,30.06263,{"lat":57,"lon":56},{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Hesham Nabil Ali Al-Qamhawy","Principal Investigator",[64],{"name":5,"class":6},"100628822",false,"NCT07466641","LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction","Effectiveness of Piezocision Versus Low-level Laser Therapy During Orthodontic Canine Retraction: A Comparative Controlled Clinical Study","Inclusion Criteria:\n\n* Age range 18-25 years.\n* Patients with crowding or protrusion requiring at least bilateral maxillary first premolar extraction followed by symmetrical canine retraction.\n* Full set of permanent dentition (third molar not considered).\n* Patients with good oral hygiene.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Patients taking medications or suffering from systemic conditions that can affect orthodontic tooth movement.\n* Active periodontal diseases and\u002For untreated carious lesions.\n* Congenital orofacial deformities.\n\nDiscontinuation criteria:\n\n* Multiple missing appointments.\n* Poor oral hygiene.\n* Multiple broken appliances to the extent that interferes with obtaining the treatment objectives.","ALL","18 Years","25 Years",{"count":75,"type":76},21,"ESTIMATED","INTERVENTIONAL",[79],"NA","This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction. Participants will be randomly assigned to one of three groups: piezocision, LLLT, or a control group (no adjunctive procedure). The study will assess the impact of these interventions on the rate of tooth movement, the type of tooth movement, and patient experience.",[82,83,84],"Malocclusion, Angle Class II, Division 1","Bimaxillary Protrusion","Class I Malocclusion",[86,87,88,89,90,91],"canine retraction","Low-level laser therapy","laser","piezocision","piezosurgery","orthodontic canine retraction","2026-05-06",{"date":94,"type":95},"2026-05-11","ACTUAL",{"date":97,"type":95},"2026-04-01",{"date":99,"type":76},"2027-06",{"name":61,"class":6},1]