About this trial

The purpose of this study was to investigate the effect of only local radical treatment of liver metastases combined with systematic treatment in the treatment of patients with multiple organ metastases of colorectal cancer, whether it can benefit the prognosis and explore the risk factors related to the prognosis.

Eligibility criteria

Qualifiers

Male or female, 18-80 years of age.

Patients volunteered to join the study and signed informed consent, with good compliance and follow-up.

Primary colorectal tumors can be radically resected or resected and histopathologically diagnosed as colorectal cancer.

Patients with synchronous or metachronous diagnosis of liver metastasis and extrahepatic metastasis by computed tomography (CT) or magnetic resonance imaging (MRI).Extrahepatic metastases are stable and controllable as determined by Multi-disciplinary Treatment (MDT).

Disqualifiers

Patients with only liver metastasis confirmed by CT or MRI.

History of hepatic encephalopathy or liver transplantation.

Evidence of brain metastases.

Pregnant or breast-feeding women.

Trial design

Treatments tested in this trial

  • Radical local Surgery
  • Systemic therapy
  • Interventional therapy

Treatment groups

130 Participants
are divided into 2 treatment groups

Locations

6
The First People's Hospital of Chu Zhou233100, ChuzhouAnhui, China
Fuyang Cancer Hospital236000, FuyangAnhui, China
Anhui province hospital230000, HefeiAnhui, China
Ma'anshan People's Hospital243000, Ma’anshanAnhui, China

Sponsors and collaborators

Anhui Provincial Hospital

Lead sponsor

First Affiliated Hospital of Wannan Medical College

Collaborator