Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorJona Hattangadi-Gluth

About this trial

In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.

Eligibility criteria

Qualifiers

Patients 18 years or older

Karnofsky performance status (KPS) ≥70

Life expectancy of ≥1 year

Primary brain tumor patients who will receive fractionated partial brain RT

Disqualifiers

Inability to undergo MRI with contrast

Prior brain RT

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 1 trial group

Locations

1
Moores Cancer Center92037, San DiegoCalifornia, United States

Sponsors and collaborators

Jona Hattangadi-Gluth

Lead sponsor

University of California, San Diego

Sponsor institution