About this trial
In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.
Eligibility criteria
Qualifiers
Patients 18 years or older
Karnofsky performance status (KPS) ≥70
Life expectancy of ≥1 year
Primary brain tumor patients who will receive fractionated partial brain RT
Disqualifiers
Inability to undergo MRI with contrast
Prior brain RT
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Locations
1Sponsors and collaborators
Jona Hattangadi-Gluth
Lead sponsor
University of California, San Diego
Sponsor institution