About this trial

Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech impairment, visual loss, dementia, and encephalopathy. The purpose of this study is to establish a research cohort to investigate the disease process, treatments, and patient outcomes in CNSV.

Eligibility criteria

Qualifiers

The presence of an acquired and otherwise unexplained neurologic deficit

The presence of either classic angiographic or histopathologic features of angiitis in the CNS

No evidence of systemic vasculitis or any condition that could cause the angiographic or pathologic features

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

6
Canada
St. Joseph's Healthcare Hamilton Canada
University of Toronto/Sinai Health Toronto Canada
United States
Mayo Clinic55905, RochesterMinnesota, United States
Cleveland Clinic44195, ClevelandOhio, United States

Sponsors and collaborators

University of Pennsylvania

Lead sponsor

The Cleveland Clinic

Collaborator