[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614465":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":19,"responsibleParty":31,"collaborators":7,"id":33,"slug":7,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":37,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":7,"studyType":45,"phases":7,"briefSummary":46,"conditions":47,"keywords":7,"overallStatus":49,"whyStopped":7,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":59},{"fullName":5,"class":6},"AstraZeneca","INDUSTRY",null,[9],{"name":10,"affiliation":11,"role":12},"Arn Migowski Rocha dos Santos","Instituto Nacional de Câncer","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"AstraZeneca Clinical Study Information Center","CONTACT","1-877-240-9479","information.center@astrazeneca.com",[20],{"facility":21,"status":7,"city":22,"state":7,"zip":23,"country":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":7},"Research Site","Rio de Janeiro","20230-130","Brazil",{"type":26,"coordinates":27},"Point",[28,29],-43.18223,-22.90642,{"lat":29,"lon":28},{"type":32,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100614465",false,"NCT07279948","Lung Cancer Screening Implementation Project in the Brazilian Public Health Care System (LUSIP)","LUSIP","Inclusion Criteria:\n\nIn order, to be eligible for the study, patients must fulfill all the following inclusion criteria:\n\n* Age between ≥50 and ≤80 years.\n* Be a current smoker or have quit 15 years ago or less.\n* Have participated or are currently participating in smoking cessation program.\n* Lifetime smoking exposure equal to or greater than 20 pack-year.\n* Provided signed informed consent (ICF)\n\nExclusion Criteria:\n\n* In order, to be exclude for the study, patients must at least one of the following exclusion criteria:\n\n  * Contraindications to the screening examination: (claustrophobic or weighing more than 130 kgs).\n  * Inability to climb 3 stair steps non-stop (36 steps).\n  * Disabling dyspnea\n  * Symptomatic (with signs and symptoms suspicious of breast cancer lung, namely):\n\n    * pleuritic chest pain\n    * rapidly progressive dyspnea of recent onset\n    * hemoptysis\n    * unexplained hoarseness, lasting more than 1 month.\n    * bone pain\n    * supraclavicular lymphadenopathy or cervical lymphadenopathy persistent\n    * unexplained weight loss of 5% or more of weight in less than 6 months\n    * Previous history of malignant neoplasm (excluding non-melanoma skin cancer) diagnosed less than 10 years before the date of the interview;\n    * Patients with diagnostic of severe psychiatric disease\n    * Immunosuppressed by illness or drugs.\n    * Subjected to anterior lung resection even when determined due to an etiology other than malignant neoplasia.\n    * Person with a serious terminal illness that contraindicates curative lung surgery.","ALL","50 Years","80 Years",{"count":43,"type":44},477,"ESTIMATED","OBSERVATIONAL","A prospective, longitudinal, single-arm interventional study of lung cancer screening.",[48],"Lung Cancer","NOT_YET_RECRUITING","2026-06-22",{"date":52,"type":53},"2026-06-25","ACTUAL",{"date":55,"type":44},"2026-06-30",{"date":57,"type":44},"2027-01-31",{"name":5,"class":6},1]