[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541112":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":54,"id":56,"slug":10,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Aarhus","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Turner Syndrome",null,"Women with karyotype verified Turner Syndrome n=100",[13,14],"Other: No intervention other than obtaining biopsies","Drug: Indocyanine green (ICG)",{"label":16,"type":10,"description":17,"interventionNames":18},"Female controls","Healthy, age-matched controls n=50",[13,14],[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"No intervention other than obtaining biopsies","Skin, fat, and muscle biopsies will be obtained",[16,9],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"DRUG","Indocyanine green (ICG)","Indocyanine green will be injected to evaluate the lymphatic system.",[16,9],[30],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Line Balsby, MD","CONTACT","+4520461203","libals@clin.au.dk",[36],{"facility":37,"status":38,"city":39,"state":10,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Aarhus University Hospital","RECRUITING","Aarhus N","8200","Denmark",{"type":43,"coordinates":44},"Point",[45,46],10.17317,56.20367,{"lat":46,"lon":45},[49,50],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},{"name":51,"role":32,"phone":10,"phoneExt":10,"email":10},"Claus Gravholt, MD, Prof.",{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[55],{"name":37,"class":6},"100541112",false,"NCT06325618","Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome","TSCOR_V","Inclusion Criteria:\n\n* Turner Syndrome\n\nExclusion Criteria:\n\n* pregnancy\n* contraindications for MRI",true,"FEMALE","18 Years","100 Years",{"count":67,"type":68},150,"ESTIMATED","OBSERVATIONAL","100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1.\n\nThe aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS.",[9,72,73,74],"Cardiovascular Diseases","Lymphedema","Inflammation","2024-03-15",{"date":77,"type":78},"2024-03-22","ACTUAL",{"date":80,"type":78},"2024-01-08",{"date":82,"type":68},"2027-08",{"name":5,"class":6},1]