[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637674":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":10,"id":38,"slug":10,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":10,"eligibilityCriteria":43,"healthyVolunteers":39,"sex":44,"minAge":45,"maxAge":10,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":53,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Elderly Surgical Patients",null,"Patients aged over 65 years who are undergoing elective non-cardiac surgery under general anesthesia with endotracheal intubation. All patients will receive continuous non-invasive hemodynamic monitoring prior to anesthesia induction to calculate baseline BRS parameters.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Quexuan Cui, Dr.","CONTACT","+8613520921711","Cuiqx_garfield@126.com",[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":22,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"RECRUITING","Beijing","China","100730",{"type":25,"coordinates":26},"Point",[27,28],116.39723,39.9075,{"lat":28,"lon":27},[31],{"name":32,"role":15,"phone":33,"phoneExt":10,"email":17},"Quexuan Cui","13520921711",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Huang YuGuang","Professor","100637674",false,"NCT07618416","Machine Learning Model Based on Baroreflex Sensitivity for Predicting Post-Induction Hypotension in Elderly Patients","Development of a Baroreflex Sensitivity-Based Multifactorial Machine Learning Model for Predicting Post-Induction Hypotension in Elderly Patients","Inclusion Criteria:\n\n* Aged over 65 years;\n* Scheduled for elective non-cardiac surgery;\n* American Society of Anesthesiologists (ASA) physical status classification I-III;\n* Planned for general anesthesia with endotracheal intubation;\n* Patient and legal guardians are capable of understanding the study protocol and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Severe peripheral vascular diseases;\n* Secondary hypertension;\n* Presence of physical tremors (e.g., Parkinson's disease) preventing stable recording;\n* Inability to accurately measure upper limb blood pressure;\n* Pre-existing cardiac arrhythmias (e.g., atrial fibrillation) that render BRS;\n* Psychiatric disorders or cognitive impairments hindering basic cooperation.","ALL","65 Years",{"count":47,"type":48},500,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to develop a high-performance machine learning model combining dynamic baroreflex sensitivity (BRS) metrics and multi-dimensional static clinical features to predict the risk of post-induction hypotension (PIH) in elderly patients undergoing elective non-cardiac surgery under general anesthesia.",[52],"Post Induction Hypotension",[54,55,56,57],"post-induction hypotension","elderly patient","baroreflex sensitivity","machine learning","2026-05-25",{"date":60,"type":61},"2026-06-01","ACTUAL",{"date":60,"type":48},{"date":64,"type":48},"2027-12-31",{"name":5,"class":6},1]