[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542217":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":33,"studyPopulation":26,"armGroups":34,"interventions":41,"overallOfficials":47,"centralContacts":51,"locations":57,"responsibleParty":73,"collaborators":26,"id":76,"slug":26,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":26,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":26,"studyType":89,"phases":90,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":60,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Kaohsiung Veterans General Hospital.","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":26},[9],{"measure":10,"description":11,"timeFrame":12},"Semen analysis","semen concentration, motility and morphology","through study completion, an average of 1 year",[14,17,20,23],{"measure":15,"description":16,"timeFrame":12},"oxygen consumption of mitochondria","oxygen consumption rate",{"measure":18,"description":19,"timeFrame":12},"mitochondrial function","adenosine triphosphate production",{"measure":21,"description":22,"timeFrame":12},"sexual function","International Index of Erectile Function (IIEF-5): a diagnostic tool for erectile dysfunction. The scores for the IIEF-5 range from 5 to 25. Higher scores mean a worse outcome",{"measure":24,"description":25,"timeFrame":12},"aging symptoms","Aging Males Symptoms Scale (AMS): a simple and effective way to detect whether you may have andropause. Each item is rated on a scale of 1 to 5. There are 17 in total, so the minimum score is 17 and the maximum score is 85. Higher scores mean a worse outcome.",null,{"allocation":28,"interventionModel":29,"interventionModelDescription":26,"primaryPurpose":30,"observationalModel":26,"timePerspective":26,"maskingInfo":31},"NA","SINGLE_GROUP","TREATMENT",{"masking":32,"maskingDescription":26,"whoMasked":26},"NONE","Due to modern lifestyle factors such as high work pressure, stressful routines, and environmental pollution, there has been a significant decline in sperm quality among men, potentially leading to infertility. In response, various supplements have emerged claiming to enhance sperm quality. This prospective investigation aims to determine the efficacy of a new supplement in improving sperm quality among patients with poor sperm quality. The study will enroll 50 patients undergoing semen analysis at our reproductive center, administering the supplement over a three-month treatment period to those identified with poor sperm quality. Subsequent semen analysis will be conducted, alongside assessments of sperm mitochondrial metabolic function before and after supplement administration. Sexual function and aging symptoms will also be evaluated using the International Index of Erectile Function (IIEF-5) and the Aging Males Symptoms Scale (AMS) before and after the supplementation period. The study aims to compare differences in semen analysis, sperm mitochondrial metabolic function, sexual function, and aging symptoms before and after supplementation.",[35],{"label":36,"type":37,"description":38,"interventionNames":39},"Male dietary supplement","EXPERIMENTAL","Patients received male supplements for a three-month treatment period",[40],"Dietary Supplement: Male supplement",[42],{"type":43,"name":44,"description":45,"armGroupLabels":46,"otherNames":26},"DIETARY_SUPPLEMENT","Male supplement","Participants will be administered supplements for a three-month treatment period",[36],[48],{"name":49,"affiliation":5,"role":50},"Kuan-Hao Tsui","STUDY_DIRECTOR",[52],{"name":53,"role":54,"phone":55,"phoneExt":26,"email":56},"Li-Te Lin","CONTACT","+88673464027","litelin1982@gmail.com",[58],{"facility":59,"status":60,"city":61,"state":26,"zip":26,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Kaohsiung Veterans General Hospital","RECRUITING","Kaohsiung City","Taiwan","TW",{"type":65,"coordinates":66},"Point",[67,68],120.31333,22.61626,{"lat":68,"lon":67},[71,72],{"name":53,"role":54,"phone":55,"phoneExt":26,"email":56},{"name":49,"role":54,"phone":26,"phoneExt":26,"email":26},{"type":74,"investigatorFullName":53,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Doctor","100542217",false,"NCT06339996","Male Supplements for Sperm Quality and Aging","To Investigate Supplements for Improving Male Sperm Quality and Combating Aging","Inclusion Criteria:\n\n* Not meet the criteria of the 6th edition of the WHO manual for human semen analysis\n* BMI:18-30 kg\u002Fm2\n\nExclusion Criteria:\n\n* Azoospermia\n* Varicocele\n* Chromosome anomaly\n* Malignancy\n* Using hormone therapy or supplements in recent 3 months",true,"MALE","30 Years","50 Years",{"count":87,"type":88},50,"ESTIMATED","INTERVENTIONAL",[28],"This study investigates the effects of a new supplement on sperm quality in men with poor sperm quality. Fifty patients will receive the supplement for three months, followed by semen analysis and assessment of sperm aging and mitochondrial function. Changes in sexual function and aging symptoms will also be evaluated.",[93],"Unrecognized Condition",[44,95,96,97,98],"Sperm quality","Aging","Mitochondrial function","Sexual function","2024-08-01",{"date":101,"type":102},"2024-08-02","ACTUAL",{"date":104,"type":102},"2024-03-26",{"date":106,"type":88},"2025-12-31",{"name":5,"class":6},1]