[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586770":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":68,"collaborators":18,"id":70,"slug":18,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":18,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":18,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group A","EXPERIMENTAL","Pregnant persons randomized into this group will be instructed to practice left-lateral recumbent position for a period of 4-hours (cumulatively) daily for 4-weeks after enrollment. The participants will be advised to stretch for 10 mins after every hour of recumbent position. A per-protocol recommendation of mild to moderate intensity exercise 2-3 times a week will be advised. A healthy diet will also be recommended. The activity at home will be recorded via a smart watch.",[13],"Behavioral: Left lateral recumbent positioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Intervention group B","NO_INTERVENTION","Pregnant persons in this group will continue to receive the 'standard of care', per clinical protocol. A recommendation of mild to moderate intensity exercise 2-3 times a week will be advised. A healthy diet will be recommended. The activity status at home will be recorded via a smart watch.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Left lateral recumbent positioning","Left-lateral position is the recommended position of resting in pregnancy. The participants in the intervention group will be advised to practice this position with an intermittent 10-minute stretching after every hour of resting, with no more than 4-hours of this intervention per day.",[9],[26],{"name":27,"affiliation":28,"role":29},"Manesha Putra, MD","University of Colorado Anschutz, Department of Obstetrics and Gynecology","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Hannah E Vincent, PhD","CONTACT","7209191019","hannah.vincent@cuanschutz.edu",[37,56],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"UCHealth Prenatal Diagnosis and Genetics Clinic - Anschutz Medical Campus","RECRUITING","Aurora","Colorado","80045","United States",{"type":45,"coordinates":46},"Point",[47,48],-104.83192,39.72943,{"lat":48,"lon":47},[51,54],{"name":52,"role":33,"phone":53,"phoneExt":18,"email":35},"Hannah E Vincent, Ph.D.","720-919-1019",{"name":55,"role":29,"phone":18,"phoneExt":18,"email":18},"Manesha Putra, M.D.",{"facility":57,"status":39,"city":58,"state":41,"zip":59,"country":43,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"CU John C. Hobbins Perinatal Center","Denver","80202",{"type":45,"coordinates":61},[62,63],-104.9847,39.73915,{"lat":63,"lon":62},[66,67],{"name":52,"role":33,"phone":53,"phoneExt":18,"email":35},{"name":55,"role":29,"phone":18,"phoneExt":18,"email":18},{"type":69,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100586770",false,"NCT06919692","Maternal Left Lateral Position in Fetal Growth Restriction","Impact of Maternal Left-Lateral Recumbent Positioning in Pregnancies With Fetal Growth Restriction","Inclusion Criteria:\n\n* Pregnant persons between 18 - 65 years of age, with a diagnosis of fetal growth restriction, with an estimated fetal weight less than tenth percentile\n* Participants with a singleton pregnancy between 24- and 34-weeks' gestational age\n* Participants with fluency in English or Spanish language\n\nExclusion Criteria:\n\n* Patients with a known history of deep vein thrombosis, pulmonary embolism, or hypercoagulability disorder\n* Patients with a pre-pregnancy BMI greater than 40\n* Pregnancy with severe abnormality in umbilical artery Doppler flow, including absent end-diastolic flow (AEDF) and reverse end-diastolic flow (REDF)\n* Patients receiving anticoagulation therapy\n* Pregnancy with suspected chromosomal anomalies or a multifetal pregnancy\n* Patients with an active smoking status during pregnancy","FEMALE","18 Years","65 Years",{"count":80,"type":81},100,"ESTIMATED","INTERVENTIONAL",[84],"NA","The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The main questions it aims to answer are:\n\n* Does maternal left-lateral position in a pregnancy with fetal growth restriction improve the baby's growth?\n* How are maternal metabolomics, delivery outcomes, maternal mental health, and fetal cardiac function impacted by maternal left-lateral position? Researchers will compare the intervention group to pregnancies with fetal growth restriction that receive standard of care (without left-lateral positioning) to see if left-lateral position improves fetal biometry in fetal growth restriction.\n\nParticipants will:\n\n* Practice left-lateral position every day for 4 hours (cumulatively) with 10-mins stretching after every hour of left-lateral position, or continue to receive standard of care\n* Visit the clinic once after 4 weeks for a follow-up research visit, and at the time of delivery\n\nTracking of the physical activity and adherence to left-lateral position at home in intervention group A will be done through a fitbit (smart watch) given during enrollment. A fitbit will also be given to participants in intervention group B, receiving standard of care, to monitor their physical activity trends at home.",[87],"Fetal Growth Restriction",[89,90,91],"fetal growth restriction","left lateral position","maternal fetal medicine","2025-07-14",{"date":94,"type":95},"2025-07-17","ACTUAL",{"date":97,"type":81},"2025-07-28",{"date":99,"type":81},"2026-12-03",{"name":5,"class":6},2]