MCE Identifying Bleeding Lesions in Patients with Antiplatelet Drugs-Related Acute Non-Hematochezia Gastrointestinal Bleeding

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChanghai Hospital

About this trial

The goal of this clinical trial is to explore the diagnostic efficacy of detachable string magnetically controlled capsule endoscopy (ds-MCE) for identification of bleeding lesions in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding. The main questions it aims to answer are:

Compared to the conventional esophagogastroduodenoscopy, does ds-MCE accurately detect bleeding lesions in the upper gastrointestinal tract in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding? Recording bleeding lesions in the small bowel detected by ds-MCE in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding.

Participants will:

Undergo ds-MCE first and subsequently EGD within 24 hours. Receive follow-up in the following 30days.

Eligibility criteria

Qualifiers

No gender limit, age ≥ 18 years;

Acute non-hematochezia gastrointestinal bleeding symptoms, including haematemesis or melena;

Taking antiplatelet drugs continuously for at least 14 days;

Hemodynamically stable;

Disqualifiers

Age < 18 years;

Hemodynamically unstable even after initial volume resuscitation and/or have ongoing fresh hematemesis at presentation;

With upper gastrointestinal bleeding caused by peptic ulcer or acute gastric mucosal lesion within 1 month before inclusion;

History of endoscopic therapy (such as ESD, EMR, etc.) within 1 month before inclusion;

Trial design

Treatments tested in this trial

  • ds-MCE and EGD examinations

Treatment groups

204 Participants
are divided into 1 treatment group

Locations

4
Qinghai Special Hospital of Cardio-Cerebrovascular Disease Qinghai China
Changhai Hospital Shanghai China
Shanghai East Hospital, Tongji University School of Medicine Shanghai China
First Affiliated Hospital Xi'an Jiaotong University Xi'an China

Sponsors and collaborators

Changhai Hospital

Lead sponsor

First Affiliated Hospital Xi'an Jiaotong University

Collaborator

Qilu Hospital of Shandong University

Collaborator