[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641834":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":54,"collaborators":26,"id":57,"slug":26,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":26,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":26,"overallStatus":73,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Meaning-Centered Psychotherapy (MCP) Dyad","EXPERIMENTAL","The MCP-Dyad arm participants will meet with an MCP-Dyad interventionist to engage in didactic content, reflection, and discussion to teach participants how to apply four sources of meaning to their lives",[13],"Behavioral: Meaning-Centered Psychotherapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","ACTIVE_COMPARATOR","The standard of care arm will receive standard resources and consultations for HSCT care, which include a joint educational class for patients and caregivers before and after treatment.",[19],"Behavioral: Usual Care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Meaning-Centered Psychotherapy","Survivor and caregiver dyads will participate in a seven-session, telehealth delivered Meaning-Centered Psychotherapy for Dyads (MCP-Dyad) program post-transplant.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Survivor and caregiver dyads will receive standard resources and consultations for hematopoietic stem cell transplantation (HSCT) care, which include a joint educational class for patients and caregivers before and after treatment.",[15],[31],{"name":32,"affiliation":5,"role":33},"Natalie McAndrew, PhD, RN","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Study Team","CONTACT","507-422-5523","rstnursingresearch@mayo.edu",[41],{"facility":5,"status":26,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Rochester","Minnesota","55905","United States",{"type":47,"coordinates":48},"Point",[49,50],-92.4699,44.02163,{"lat":50,"lon":49},[53],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},{"type":33,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Natalie S. McAndrew, PhD, RN","Principal Investigator","100641834",false,"NCT07595146","Meaning-Centered Psychotherapy for Addressing Existential Distress of Patient\u002FCaregiver Dyads Following Hematopoietic Stem Cell Transplantation: Feasibility and Acceptability","Inclusion criteria:\n\n* Eligible patients and their caregivers must be adults (≥18 years)\n* Patient must have undergone HSCT for a malignant blood cancer condition\n* Caregiver must be the main support person (e.g., signed caregiving contract) for the HSCT patient\n* Both the patient and their caregiver must be willing to participate in the study (dyads only)\n* Be able to read, write, and speak in English\n* Have access to a smartphone, computer, or tablet necessary for study participation and assessments. If a patient\u002Fcaregiver dyad is interested in participating but does not have such a device, we will provide a Tracfone with smartphone capabilities for each member of the dyad\n\nExclusion criteria:\n\n* Patients undergoing HSCT for nonmalignant conditions\n* Patients and caregivers with severe cognitive or psychiatric impairment that may affect informed consent\u002Fparticipation\n* Prisoners, pregnant women, and institutionalized persons\n* Patients with severe cognitive or psychiatric impairment that would affect informed consent or participation","ALL","18 Years",{"count":65,"type":66},100,"ESTIMATED","INTERVENTIONAL",[69],"NA","The purpose of this study is to learn whether Meaning-Centered Psychotherapy (MCP-Dyad) is practical, acceptable, and helpful to survivors and caregivers during recovery after stem cell transplant. MCP-Dyad is a meaning-focused support program. It is designed to help people stay connected to meaning, cope with difficult experiences, and communicate as a pair during recovery.",[72],"Hematopoietic Stem Cell Transplant","NOT_YET_RECRUITING","2026-06-17",{"date":76,"type":77},"2026-06-22","ACTUAL",{"date":79,"type":66},"2026-08-01",{"date":81,"type":66},"2028-04-30",{"name":5,"class":6},1]