[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100363625":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":51,"collaborators":10,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Norfolk and Norwich University Hospitals NHS Foundation Trust","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Event-free",null,"Patients who have had no negative events (as described in group 2)",{"label":13,"type":10,"description":14,"interventionNames":10},"Negative event","Group 2 - patients with one or more of the following negative events post-operatively:\n\n* Whether the patient has been prescribed inotropic support\n* Wound infection by assessing use of antibiotics.\n* Length of stay in hospital \\>1 week\n* Reduced renal function assessed by having any AKI alert during hospital stay\n* Cardiac event within 31 days following surgery\n* Death within 31 days following surgery",[16],{"name":17,"affiliation":18,"role":19},"Emma Miler, MSc BSc Hons","principle investigator","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+44(0)1603-286-932","emma.miler@nnuh.nhs.net",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Allison Chipchase, Dr","+44(0)1603-286-929","allison.chipchase@nnuh.nhs.net",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Norfolk & Norwich University Hospitals NHS Foundation Trust","RECRUITING","Norwich","Norfolk","NR4 7UY","United Kingdom",{"type":38,"coordinates":39},"Point",[40,41],1.29834,52.62783,{"lat":41,"lon":40},[44,47],{"name":26,"role":22,"phone":45,"phoneExt":10,"email":46},"+44 1603 287945","allison\u002Fchipchase@nnuh.nhs.uk",{"name":48,"role":22,"phone":49,"phoneExt":10,"email":50},"Emma Miler","+44 1603 286392","emma.miler@nnuh.nhs.uk",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100363625",false,"NCT04014647","Measurement Of NT-proBNP to Predict Outcomes in Surgery","Peri-operative Measurement of NT-proBNP to Predict Outcomes in Patients Undergoing Elective Vascular Surgery","MOBOS","Inclusion Criteria:\n\n* Patients who are equal to or over 18 years old\n* Patients scheduled to undergo elective surgery for the following procedures:\n* Infrainguinal arterial reconstruction\n* Aortic aneurysm\n* Aorto-bifemoral bypass \u002F or aortic endarterectomy\n* Femoro-popliteal bypass\n* Femoro-distal bypass\n* Femoral endarterectomy\n* Femoro-femoral crossover\n* Axillo-femoral bypass\n* Elective carotid surgery\n* Patients having either general or regional anaesthesia for their surgery\n\nExclusion Criteria:-\n\n* Patients undergoing emergency surgery\n* Those who are unable or unwilling to give informed consent\n* Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris)\n* Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy)\n* Patients with chronic atrial fibrillation","ALL","18 Years",{"count":63,"type":64},200,"ESTIMATED","OBSERVATIONAL","The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determine which patients are at risk of an adverse outcome, such as a heart attack or death.",[68],"Vascular Surgical Procedure",[68,70,71,72,73,74,75],"Pro-brain natriuretic peptide (1-76)","Natriuretic Peptide, Brain","Troponin I","Galectin 3","Biomarkers","Risk","2026-06-05",{"date":78,"type":79},"2026-06-08","ACTUAL",{"date":81,"type":79},"2019-09-05",{"date":83,"type":64},"2029-09-05",{"name":5,"class":6},1]