[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100381033":3},{"organization":4,"outcomesModule":7,"designInfo":17,"detailedDescription":20,"studyPopulation":21,"armGroups":16,"interventions":16,"overallOfficials":16,"centralContacts":22,"locations":28,"responsibleParty":191,"collaborators":16,"id":193,"slug":16,"hasResults":194,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":198,"eligibilityCriteria":199,"healthyVolunteers":194,"sex":200,"minAge":16,"maxAge":16,"enrollmentInfo":201,"targetDuration":204,"studyType":205,"phases":16,"briefSummary":206,"conditions":207,"keywords":16,"overallStatus":31,"whyStopped":16,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":218},{"fullName":5,"class":6},"Medtronic Cardiac Surgery","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":16},[9,13],{"measure":10,"description":11,"timeFrame":12},"Device Safety","Procedure- , device-related events and device deficiencies","Procedural",{"measure":14,"description":15,"timeFrame":12},"Device performance","Device Success",null,{"allocation":16,"interventionModel":16,"interventionModelDescription":16,"primaryPurpose":16,"observationalModel":18,"timePerspective":19,"maskingInfo":16},"OTHER","PROSPECTIVE","The objective is to collect product safety and performance data for Medtronic CE (Conformitè Europëenne )-Marked Cardiac Surgery, including perfusion (CS) products.\n\nThe main goals of this data collection are as follows:\n\n* Identification of any (new) device-related complications including events which were not anticipated or documented in the Instructions For Use (IFU), or Risk Management Plan, or Clinical Evidence Evaluation report, or Design Failure Modes and Effect Analysis\n* Evaluation of device success defined as the absence of any probable or causal device-related adverse events or device deficiencies\n* Evaluation of general device performance when applicable\n\nSubjects are enrolled and, if applicable, followed according to routine care practices at their treating hospital.\n\nInclusion Criteria:\n\n* Subject or legally authorized representative provides written data release and\u002For informed consent per institution and\u002For geographical requirements prior to discharge from participating Registry hospital.\n* Subject will undergo or underwent a procedure in which an eligible Medtronic CS product is\u002Fwas used.\n\nExclusion Criteria:\n\n• Currently participating in an interventional drug or device study which may induce confounding factor(s) to the results from this Registry\n\nData collection includes, for example:\n\n* Demographics\n* Product performance information\n* Safety Events","All consecutive subjects with the intent of being treated or treated (up to discharge from treating hospital) with a market-approved Medtronic CS product, are candidates to be enrolled. The Investigator will determine subject eligibility in SYMBIOSIS based upon the inclusion\u002Fexclusion criteria. If a subject meets all inclusion and none of the exclusion criteria, they will be informed about the SYMBIOSIS Registry. SYMBIOSIS will collect data of numerous patient conditions for which Medtronic CS products are being used.",[23],{"name":24,"role":25,"phone":26,"phoneExt":16,"email":27},"Lisa Lindelauf, BSc","CONTACT","+31611605434","lisa.lindelauf@medtronic.com",[29,45,59,70,81,91,104,115,127,138,149,158,169,180],{"facility":30,"status":31,"city":32,"state":16,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"AKH Wien","RECRUITING","Vienna","1090","Austria","AT",{"type":37,"coordinates":38},"Point",[39,40],16.37208,48.20849,{"lat":40,"lon":39},[43],{"name":44,"role":25,"phone":16,"phoneExt":16,"email":16},"D Wiedemann, Prof. Dr.",{"facility":46,"status":31,"city":47,"state":16,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"Ziekenhuis Oost-Limburg","Genk","3600","Belgium","BE",{"type":37,"coordinates":52},[53,54],5.50082,50.965,{"lat":54,"lon":53},[57],{"name":58,"role":25,"phone":16,"phoneExt":16,"email":16},"Christiaan 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München","Munich","80636",{"type":37,"coordinates":120},[121,122],11.57549,48.13743,{"lat":122,"lon":121},[125],{"name":126,"role":25,"phone":16,"phoneExt":16,"email":16},"Keti Vitanova, Dr. med.",{"facility":128,"status":129,"city":130,"state":16,"zip":16,"country":131,"countryCode":132,"cosmosGeoPoint":133,"geoPoint":137,"contacts":16},"Onassis Hospital","ACTIVE_NOT_RECRUITING","Athens","Greece","GR",{"type":37,"coordinates":134},[135,136],23.72784,37.98376,{"lat":136,"lon":135},{"facility":139,"status":72,"city":140,"state":16,"zip":141,"country":142,"countryCode":143,"cosmosGeoPoint":144,"geoPoint":148,"contacts":16},"Catharina Ziekenhuis","Eindhoven","5623 EJ","Netherlands","NL",{"type":37,"coordinates":145},[146,147],5.47778,51.44083,{"lat":147,"lon":146},{"facility":150,"status":129,"city":151,"state":16,"zip":152,"country":142,"countryCode":143,"cosmosGeoPoint":153,"geoPoint":157,"contacts":16},"Maastricht University Medical Center (MUMC+)","Maastricht","6229 HX",{"type":37,"coordinates":154},[155,156],5.68889,50.84833,{"lat":156,"lon":155},{"facility":159,"status":31,"city":160,"state":16,"zip":16,"country":142,"countryCode":143,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"St. Antonius Ziekenhuis","Nieuwegein",{"type":37,"coordinates":162},[163,164],5.08056,52.02917,{"lat":164,"lon":163},[167],{"name":168,"role":25,"phone":16,"phoneExt":16,"email":16},"Dr. Guillaume Geuzebroek",{"facility":170,"status":171,"city":172,"state":16,"zip":16,"country":173,"countryCode":174,"cosmosGeoPoint":175,"geoPoint":179,"contacts":16},"Haukeland Universitetssjukehus","SUSPENDED","Bergen","Norway","NO",{"type":37,"coordinates":176},[177,178],5.32415,60.39299,{"lat":178,"lon":177},{"facility":181,"status":72,"city":182,"state":16,"zip":183,"country":184,"countryCode":185,"cosmosGeoPoint":186,"geoPoint":190,"contacts":16},"Hospital Clinic Barcelona","Barcelona","08036","Spain","ES",{"type":37,"coordinates":187},[188,189],2.15899,41.38879,{"lat":189,"lon":188},{"type":192,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR","100381033",false,"NCT04241328","Medtronic SYMBIOSIS Post-Market Registry for Patients Undergoing Cardiac Surgery","SYMBIOSIS Post-Market Registry","SYMBIOSIS","Inclusion Criteria:\n\n* Subject or legally authorized representative provides written data release and\u002For informed consent per institution and\u002For geographical requirements prior to discharge from participating registry hospital.\n* Subject will undergo or underwent a procedure in which an eligible Medtronic CS product is\u002Fwas used.\n\nExclusion Criteria:\n\n* Currently participating in an interventional drug or device study which may induce confounding factor(s) to the results from this Registry","ALL",{"count":202,"type":203},5000,"ESTIMATED","30 Days","OBSERVATIONAL","The purpose of this observational, multi-center prospective, post-market registry is to confirm real-world device safety and performance, to ensure the continued acceptability of identified risks, and detect emerging risks.",[208],"Cardiovascular Diseases","2026-06-08",{"date":211,"type":212},"2026-06-09","ACTUAL",{"date":214,"type":212},"2020-01-09",{"date":216,"type":203},"2026-12-31",{"name":5,"class":6},14]