Health Trials

About this trial

The goal of this clinical trial is to learn if melatonin will decrease pain after C.S. The main questions it aims to answer are:

Does melatonin lower the number of times participants need to use a rescue analgesia? What medical problems do participants have when taking melatonin? Researchers will compare different doses of melatonin to see the ideal dose to decrease pain after C.S.

Participants will:

Take melatonin 30 min before C.S and will be observed for 24 hours for pain and consumption of other analgesia

Eligibility criteria

Qualifiers

- Women aged 18-40 years.

Scheduled for elective cesarean section.

Ability to provide informed consent.

Disqualifiers

Known hypersensitivity to melatonin or opioids

Chronic use of analgesics, sedatives, or antidepressants.

History of sleep disorders or psychiatric illness.

Complicated pregnancies (e.g., preeclampsia, gestational diabetes).

Trial design

Treatments tested in this trial

  • Melatonin 5 mg
  • Melatonin 10 mg
  • Placebo

Treatment groups

60 Participants
are divided into 3 treatment groups

Locations

1
Benha University Hospital Banhā Egypt

Sponsors and collaborators

Benha University

Lead sponsor

Source ClinicalTrials.gov