Health Trials

About this trial

Women and men show marked differences in cardiovascular risk profile and outcome. Women experience fewer cardiovascular events than men before menopause, but this relationship seems to reverse at menopause. These disparities are probably due to hormonal factors, especially the female sex hormone estrogen seems to have a protective influence on the development of atherosclerotic plaques premenopausal.

The underlying mechanisms of the effect of estrogens on the vessel wall are still insufficiently investigated. In this study, menopause related effects on leukocyte distribution and function as well on platelets and their aggregational response will be evaluated.

Eligibility criteria

Qualifiers

Age > 18 years

Male, female, diverse patients with current treatment in the Department of Cardiology, Pneumology and Angiology.

Persons who are able to understand and follow the instructions of the study staff

Written informed consent

Disqualifiers

Age < 18 years

Lack of written consent to participate in the study

coagulation disorders

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

1
University-Hospital Düsseldorf Division of Cardiology, Pulmonary Disease and Vascular Medicine40225, Düsseldorf Germany

Sponsors and collaborators

Heinrich-Heine University, Duesseldorf

Lead sponsor

Source ClinicalTrials.gov