[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573239":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":19,"interventions":13,"overallOfficials":26,"centralContacts":31,"locations":13,"responsibleParty":39,"collaborators":41,"id":52,"slug":13,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":13,"enrollmentInfo":61,"targetDuration":13,"studyType":64,"phases":13,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":74,"whyStopped":13,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":13},{"fullName":5,"class":6},"University College Dublin","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Qualitative interview, focus group, and brief questionnaire findings","The primary outcome will the findings of in-depth semi-structured qualitative interviews, focus groups, and brief questionnaires with a purposive sample of patients and HCPs who participated in the META trial (n=50-60).","8 weeks",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"CASE_ONLY","CROSS_SECTIONAL","The META trial was a phase II randomised double-blind placebo-controlled trial that is being conducted in Dar es Salaam, Tanzania to evaluate the use of metformin in HIV-positive persons on antiretroviral therapy (ART) with pre-diabetes.\n\nThis study aims to explore the feasibility, acceptability and perceived effectiveness of the META trial intervention by conducting qualitative interviews, focus groups, and brief questionnaires with a purposive sample of participants (patients and healthcare providers) in Tanzania who are involved in the META trial.\n\nData collection will commence during June-July 2025 with a purposive sample of patients and health care professionals who were involved in the trial (n=50-60).","All participants that took part in the META trial will be able to participate in this study. Not all participants involved in the META trial will be included in this study. However, participants will be purposefully sampled to be reflective of the population who participated in the META trial.",[20,23],{"label":21,"type":13,"description":22,"interventionNames":13},"Patients","Patients that participated in the META trial.",{"label":24,"type":13,"description":25,"interventionNames":13},"Healthcare staff","Healthcare staff that were involved in the META trial.",[27],{"name":28,"affiliation":29,"role":30},"Walter Cullen, MD","UCD NUI: University College Dublin","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":13,"email":36},"John M Broughan, MSc","CONTACT","+353868928972","john.broughan@ucd.ie",{"name":28,"role":34,"phone":13,"phoneExt":13,"email":38},"walter.cullen@ucd.ie",{"type":40,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR",[42,45,48,50],{"name":43,"class":44},"University College London Institute for Global Health","UNKNOWN",{"name":46,"class":47},"National Institute for Medical Research, Tanzania","OTHER_GOV",{"name":49,"class":44},"Shree Hindu Mandal Hospital, Tanzania",{"name":51,"class":6},"Barcelona Institute for Global Health","100573239",false,"NCT06743698","META Trial - a Mixed Methods Process Evaluation","A Mixed Methods Process Evaluation of a Randomised Controlled Trial (META Trial) to Evaluate the Use of Metformin in HIV-Positive Persons With Pre-Diabetes","META","Inclusion Criteria:\n\n* Participants who participated in the META Trial\n* Participants who have the capacity to provide written informed consent","ALL","18 Years",{"count":62,"type":63},60,"ESTIMATED","OBSERVATIONAL","The aim of this study is to conduct a mixed methods process evaluation of the META trial. Semi-structured interviews, focus groups, and brief questionnaires will be conducted with a purposive sample of participants (patients and healthcare providers) who were involved in the trial to explore the feasibility, acceptability and perceived effectiveness of the trial intervention.",[67,68],"HIV","Pre-diabetes",[70,71,72,73,67,68],"Qualitative Research","Process evaluation","Metformin","Africa","NOT_YET_RECRUITING","2025-04-08",{"date":77,"type":78},"2025-04-11","ACTUAL",{"date":80,"type":63},"2025-06-01",{"date":82,"type":63},"2027-02",{"name":5,"class":6}]