[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554520":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":22,"studyPopulation":26,"armGroups":27,"interventions":32,"overallOfficials":22,"centralContacts":37,"locations":46,"responsibleParty":74,"collaborators":22,"id":77,"slug":22,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":22,"enrollmentInfo":86,"targetDuration":22,"studyType":89,"phases":22,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":49,"whyStopped":22,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Corporacion Parc Tauli","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":22},[9],{"measure":10,"description":11,"timeFrame":12},"VO2-response","Percentage increase in VO2 as results of the fluid challenge","30 minutes",[14,18],{"measure":15,"description":16,"timeFrame":17},"Organ failure","Assessment of the SOFA score at day 1, 2 and 4","4 days",{"measure":19,"description":20,"timeFrame":21},"Mortality","Mortality within the first 28 days","28 days",null,{"allocation":22,"interventionModel":22,"interventionModelDescription":22,"primaryPurpose":22,"observationalModel":24,"timePerspective":25,"maskingInfo":22},"COHORT","PROSPECTIVE","Septic shock patients within the first 24 hours of ICU admission, and selected by the attending physician for performing a fluid challenge (FC) due to suspected tissue hypoperfusion.",[28],{"label":29,"type":22,"description":26,"interventionNames":30},"Septic shock",[31],"Other: Fluid challenge",[33],{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":22},"Fluid challenge","Rapid infusion (\\\u003C 15 minutes) of a fluid bolus of crystalloids (200 to 500cc)",[29],[38,43],{"name":39,"role":40,"phone":41,"phoneExt":22,"email":42},"Jaume Mesquida, MD","CONTACT","+34937231010","jaume.mesquida@gmail.com",{"name":44,"role":40,"phone":22,"phoneExt":22,"email":45},"Ferran Oller, MD","ferranollersanchez@gmail.com",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Hospital Universitari Parc Taulí","RECRUITING","Sabadell","Barcelona","08208","Spain","ES",{"type":56,"coordinates":57},"Point",[58,59],2.10942,41.54329,{"lat":59,"lon":58},[62,63,64,66,67,70,72],{"name":39,"role":40,"phone":41,"phoneExt":22,"email":42},{"name":44,"role":40,"phone":22,"phoneExt":22,"email":45},{"name":44,"role":65,"phone":22,"phoneExt":22,"email":22},"PRINCIPAL_INVESTIGATOR",{"name":39,"role":65,"phone":22,"phoneExt":22,"email":22},{"name":68,"role":69,"phone":22,"phoneExt":22,"email":22},"Sara Nogales, MD","SUB_INVESTIGATOR",{"name":71,"role":69,"phone":22,"phoneExt":22,"email":22},"Edgar Cortés, MD",{"name":73,"role":69,"phone":22,"phoneExt":22,"email":22},"Guillem Gruartmoner, MD",{"type":65,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Jaume Mesquida","Principal Investigator","100554520",false,"NCT06500156","Metabolic Cluster Analysis in Septic Shock Patients","Metabolic Cluster Analysis in Septic Shock Patients Undergoing Hemodynamic Resuscitation. A Multicenter Observational Study","ACMEcat","Inclusion Criteria:\n\n\\- Septic shock patients within the first 24 hours of ICU admission, and selected by the attending physician for performing a fluid challenge (FC) due to suspected tissue hypoperfusion (elevated lactate and\u002For ScvO2 \\\u003C 70%).\n\nExclusion Criteria:\n\n* Age under 18 years old\n* Uncontrolled hemodynamic instability, defined as the need for significant changes in vasopressor support (\\> 10% from baseline dose) within the 15-minute period prior to, and\u002For during the administration of fluids.\n* Patients receiving continuous renal replacement therapies, since the CO values obtained from the thermodilution techniques might be potentially affected.","ALL","18 Years",{"count":87,"type":88},120,"ESTIMATED","OBSERVATIONAL","Observational study including septic shock patients within 24 hours of ICU admission, monitored with a cardiac output estimation system, with ongoing resuscitation. Hemodynamic and metabolic parameters before and after a fluid challenge (FC) will be measured.",[92],"Septic Shock",[94,95,96],"septic shock","hemodynamic resuscitation","cardiovascular monitoring","2025-11-28",{"date":99,"type":100},"2025-12-05","ACTUAL",{"date":102,"type":100},"2024-05-01",{"date":104,"type":88},"2026-10-31",{"name":5,"class":6},1]