Metabolic Health, Bones and Nuts During Weight Loss in Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-75
SponsorRutgers, The State University of New Jersey

About this trial

The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain, and several dietary pattern studies indicate that nuts and legumes are associated with better bone health. In addition, our preliminary translational data indicates that a higher monounsaturated fatty acid (MUFA) intake is associated with improved bone mineral density (BMD) and quality. Given these findings, the proposed study aims to examine the impact of consuming peanut products on bone health, metabolic health (e.g., serum glucose, insulin, lipids and inflammation), markers of brain and sleep health, and physical function in overweight and obese older adults before and after a six-month weight loss intervention using a randomized controlled design. The results of this study have the potential to provide valuable insights into the role of peanuts as a sources of fatty acids in promoting health and preventing disease in at-risk adults.

Eligibility criteria

Qualifiers

Men and postmenopausal women (>2 years since last menses), ages 50-75 years

Body mass index (25-42 kg/m2) or evidence of pre-clinical obesity.

Agree to be randomly assigned to consume a daily peanut snack or nut-free snack for 24 weeks

Must attend on-site visits (about 10) in New Brunswick, NJ, USA (transportation/reimbursement for travel not included)

Disqualifiers

Peanut allergies or intolerances

Participants with >5% weight loss in the past 6 months or extreme dietary/physical activity habits

An inability to follow the experimental intervention or to perform the required specimen collections.

Individuals with significant psychiatric or food disorders.

Trial design

Treatments tested in this trial

  • Peanut Snack Experimental
  • Nut-free Snack

Treatment groups

44 Participants
are divided into 2 treatment groups

Locations

1
Rutgers University - NJ Inst Food Nutrition & Health08901, New BrunswickNew Jersey, United States

Sponsors and collaborators

Rutgers, The State University of New Jersey

Lead sponsor