The aim of the prospective observational DISTEMI-Study in people with and without Diabetes mellitus (DI) after new onset of ST-Segment Elevation Myocardial Infarction (STEMI) aged 18-80 years at inclusion into the study is to characterize in detail the clinical, metabolical, immunological and vascular phenotype, investigate the interplay between myocardial remodelling and the metabolic phenotype, monitor the progression of the disease and compare the phenotype of STEMI people with diabetes mellitus to people with prediabetes and glucose tolerant people.
Condition after new onset of ST-segment elevation myocardial infarction (STEMI)
Age 18-80 years
HbA1c <9.0%
People with diagnosis of diabetes mellitus according to ADA and DDG criteria (i.e. HbA1c ≥6.5% and/or pathological oral glucose tolerance test)
Diabetes mellitus category 3 A-H (ADA criteria), gestational diabetes
Current pregnancy
Infectious diseases, acute infections / fever
Immunosuppressive therapy
German Diabetes Center
Lead sponsor