[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602656":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":48,"collaborators":52,"id":82,"slug":10,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":96,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":102,"overallStatus":106,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Buzzi Children's Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Permanent congenital hypothyroidism",null,"170 patients in prepubertal age.",[13],"Other: prospective observational study (clinical, hormonal and auxological data)",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy childrens normal weight","170 childrens in prepubertal age.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy childrens overweight\u002Fobese","170 patients in prepubertal age",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"prospective observational study (clinical, hormonal and auxological data)","We collect clinical, hormonal and auxological data and compare them between the two groups.",[15,19,9],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Valeria Calcaterra, MD","CONTACT","+39 0263631","valeria.calcaterra@unipv.it",[34],{"facility":5,"status":10,"city":35,"state":10,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Milan","20154","Italy",{"type":39,"coordinates":40},"Point",[41,42],12.59836,42.78235,{"lat":42,"lon":41},[45],{"name":46,"role":30,"phone":47,"phoneExt":10,"email":32},"Valeria Calcaterra, Prof, MD","00390263635321",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Valeria Calcaterra","Prof",[53,55,57,60,62,64,66,68,70,72,74,76,78,80],{"name":54,"class":6},"Federico II University",{"name":56,"class":6},"IRCCS Ospedale San Raffaele",{"name":58,"class":59},"Policlinico di Bari Giovanni XXIII","UNKNOWN",{"name":61,"class":6},"Azienda Ospedaliero Universitaria Policlinico Modena",{"name":63,"class":6},"Azienda Ospedaliero-Universitaria di Parma",{"name":65,"class":6},"Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna",{"name":67,"class":6},"Azienda Ospedaliera Sant'Anna",{"name":69,"class":59},"University Hospital Perugia",{"name":71,"class":6},"University of L'Aquila",{"name":73,"class":59},"Clinica Pediatrica Università di Novara",{"name":75,"class":59},"Santobono-Pausilpon Hospital",{"name":77,"class":59},"Policlinico G . Martino, Messina Italy",{"name":79,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"name":81,"class":59},"University Hospital of Ancona","100602656",false,"NCT07126353","Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism","Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism (IpoMet)","IpoMet","Inclusion Criteria:\n\n* Pubertal stage Tanner 1\n* Permanent congenital hypothyroidism\n* All ethnic groups\n* Informed consent signature\n\nExclusion Criteria:\n\n* Age\\\u003C 5 years\n* Pubertal stage Tanner 2-5\n* Transient congenital hypothyroidism or other type of hypothyroidism",true,"ALL","5 Years","12 Years",{"count":94,"type":95},170,"ESTIMATED","12 Months","OBSERVATIONAL","We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric population. These data will help to define whether hypothyroidism can be considered a risk factor for the metabolic health of the pediatric population. The possible identification of an at-risk metabolic profile will provide useful information to optimize the diagnostic and monitoring pathway for affected children.",[100,101],"Congenital Hypothyroidism","Metabolic Syndrome",[103,104,105],"Congenital hypothyroidism","metabolic syndrome","Obesity","NOT_YET_RECRUITING","2025-08-10",{"date":109,"type":110},"2025-08-17","ACTUAL",{"date":112,"type":95},"2025-09",{"date":114,"type":95},"2026-10",{"name":5,"class":6},1]